Genics

Question 1

What is autosomal dominant inheritance?

Answer 1

at least one parent carries the gene that is expressed.

Question 2

What is autosomal recessive inheritance?

Answer 2

both parents carry gene that is being expressed.

Question 3

X-link recessive inheritance affects who more?

Answer 3

-affects males mostly

Question 4

X-link dominant affects who more?

Answer 4

females

Question 5

Y-linked inheritance only affects?

Answer 5

males

Question 6

Mitochondrial inheritance results from?

Answer 6

the maternal egg

Question 7

What are SNPs?

Answer 7

single nucleotide polymorphisms

Question 8

MTHFR is related to what nutrient?

Answer 8

folate

Question 9

What happens with MTHFR?

Answer 9

affects methylation

Question 10

What is methylation?

Answer 10

a chemical reaction where a methyl group gets added to DNA, proteins or other modules.

Question 11

What is pharmacogenomics?

Answer 11

used to predict how a patient might respond to drug

Question 12

What is epigenetic?

Answer 12

gene expression is controlled by epigenetic marks, which determines function or expression of the gene

Question 13

What is mendelian inheritance?

Answer 13

track a mutation through family history

Question 14

What is trisomy or down syndrome?

Answer 14

-chromosomal disorder
-determined karyotype
-addition of chromosome material to chromosomes 21

Question 15

PKU results from?

Answer 15

-mutation in the gene coding for the enzymes phenylalanine hydroxylase
-can’t convert phenylalanine to tyrosine

Question 16

Maple syrup urine disease can cause what?

Answer 16

seizures