Gen Bio Membrane Structure and function Flashcards

1
Q

fluid mosaic, with protein molecules embedded in a phospholipid bilayer.

A

Membranes

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2
Q
  • Mosaic denotes
A

surface made of small pieces

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3
Q

A membrane is a “mosaic” in having

A

diverse protein molecules embedded

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4
Q

What keeps a membrane “fluid”?

A

-Kinks in the unsaturated fatty acid tails of some phospholipids
- cholesterol (in animal cells)

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5
Q

a cell may alter the molecular composition of its membranes as an adaptation to changing ___________

A

temperature

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6
Q

How do plants keeps the membranes from crystallizing during winter

A

increase their percentage of unsaturated phospholipids

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7
Q

membranes of certain hibernating animals are enriched in ___________

A

cholesterol,

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8
Q

Functions of Membrane Proteins

A
  • Transport
  • Enzymatic Activity
  • Sigmal Transduction
  • Cell-to-Cell recognition
  • Intercellular Joining
  • Attachment
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9
Q

the concept that allows some substances to cross more easily than others.

A

selective permeability

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10
Q

What are found in the ECM

A
  • Cholesterol, Carbohydrates, Proteins, Lipids, Glycolipids, Glycoproteins
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11
Q

2 Types of Proteins found in the Membrane

A
  • Integral Protein
  • Peripheral Protein
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12
Q

Proteins embedded in the membrane

A

Integral Proteins

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13
Q

proteins on the surface of membrane (on the cytoplasmic side)

A

peripheral proteins

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14
Q

Protein that functions in attachment; found in ECM attached by intermediate filaments

A

integrin

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15
Q

functions of membrane utilizing a signalling molecule attaching to receptor that will cause a change/response within cells

A

Sigmal Transduction

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16
Q

“glyco” used as __________ for recognition

A

markers

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17
Q

Function of Membrane that involves junctions and joining

A

Intercellular Joining

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18
Q

Function of Membrane in which enzymes embedded react to substrates

A

Enzymatic Act.

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19
Q

Reason for Selective Permeability of membranes

A
  • hydrophobic interior
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20
Q

___________, hydrophobic molecules can easily pass-through membranes.

A

Nonpolar

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21
Q

_____ and ______ are not soluble in lipids (may require transport proteins to enter or leave the cell).

A

Polar molecules and ions

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22
Q

DIFFUSION ACROSS A MEMBRANE WITH NO ENERGY INVESTMENT

A

PASSIVE TRANSPORT

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23
Q

movement of molecules from an area where they are in high concentration to an area where the molecules are in low concentration

A

Diffusion

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24
Q

Because a cell does not have to do work when molecules diffuse across its membrane, such movement is called ___________

A

passive transport.

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25
DIFFUSION OF WATER ACROSS A MEMBRANE
osmosis
26
refers to the ability of a surrounding solution to cause a cell to gain or lose water.
tonicity
27
The tonicity of a solution mainly depends on its concentration of________relative to the concentration of _________ inside the cell.
solutes ;solutes
28
When an animal cell, is immersed in a solution that is __________ to the cell, the cell’s volume remains constant.
isotonic
29
solute concentration of a cell and its isotonic environment are essentially equal, and the cell gains water at the same rate that it loses it.
isotonic
30
What happens when an animal cell is placed in a hypotonic solution
gains water, swells, and may burst (lyse)
31
an animal cell placed in a hypertonic solution will
shrivel and die from water loss
32
an animal cell placed in a hypertonic solution will
shrivel and die from water loss
33
solution that has lower solute concentration than a cell
hypotonic
34
solution with higher solute concentration
hypertonic
35
In a hypotonic environment, a plant cell is __________ which is the healthy state for most plant cells.
turgid (very firm),
36
. Although the plant cell swells as water enters by osmosis, the cell wall exerts a back pressure, called ____________, which prevents the cell from taking in too much water and bursting.
turgor pressure
37
When a plant cell is surrounded by an isotonic solution, what happens?
there is no net movement of water into the cell, and the cell is flaccid (limp).
38
In a hypertonic environment, a plant cell is no better off than an animal cell. As a plant cell loses water, it __________
shrivels, and its plasma membrane pulls away from the cell wall.
39
How do polar or charged substances make it past the hydrophobic center of a membrane?
the help of specific transport proteins in a process called facilitated diffusion
40
In all passive transport, the driving force is the __________
concentration gradient.
41
2 types of transport protein structure
- Channel proteins - Carrier Proteins
42
After osmosis, water moves in equal rates which is called
dynamic equilibrium
43
Another type of transport protein, that binds its passenger, changes shape, and releases the transported molecule on the other side.
carrier proteins
44
Substances that use facilitated diffusion for crossing cell membranes include
sugars, amino acids, ions—and even water.
45
the very rapid diffusion of water into and out of such cells is made possible by a protein channel called an ________
aquaporin
46
cell must expend energy to move a solute against its concentration gradient—
active transport
47
what supplies energy for most active transport
ATP
48
Example of ACtive transport
Sodium-Potassium pump - higher potassium needed inside and lesser sodium
49
A cell uses the process of __________to export bulky materials such as proteins or polysaccharides.
exocytosis (from the Greek exo, outside, and kytos, cell)
50
A _________ buds from the Golgi apparatus and moves to the edge of the cell, where it fuses with the plasma membrane to transport substances.
transport vesicle
51
a transport process through which a cell takes in large molecules or droplets of fluid.
Endocytosis
52
What needs to be overcome before a chemical reaction can begin
Energy Barrier
53
Energy must be absorbed to contort or weaken bonds in reactant molecules so that they can break and new bonds can form. We call this the __________
activation energy (because it activates the reactants).
54
Bulk transport that increases cell's surface area
exocytosis
55
what speeds up the cell’s chemical reactions by lowering energy barriers.
enzymes
56
molecules that function as biological catalysts, increasing the rate of a reaction without being consumed by the reaction.
enzymes
57
Structure of an enzyme
unique three-dimensional shape, and that shape determines the enzyme’s specificity
58
The specific reactant that an enzyme acts on is called the
enzyme's substrate
59
A substrate fits into a region of the enzyme called the ________
active site
60
Enzymes are specific because _________
only specific substrate molecules fit into their active sites.
61
Optimal Temp and pH of an enzyme
35-40 deg cel pH 6-8 9(except pepsin ph2)
62
Many enzymes require nonprotein helpers called __________which bind to the active site and function in catalysis.
cofactors,
63
T or F. The cofactors of some enzymes are organic
T coenzymes
64
If the cofactor is an organic molecule, it is called a _________
coenzyme.
65
___________ BLOCK ENZYME ACTION AND CAN REGULATE ENZYME ACTIVITY IN A CELL
ENZYME INHIBITORS
66
chemical that interferes with an enzyme’s activity
inhibitors
67
reduces an enzyme’s productivity by blocking substrate molecules
competitive inhibitor
68
Competitive inhibition can be overcome by
increasing the concentration of the substrate
69
does not enter the active site. Instead, it binds to a site elsewhere on the enzyme, and its binding changes the enzyme’s shape so that the active site no longer fits the substrate
noncompetitive inhibitor
70
_FEEDBACK INHIBITION HELPS REGULATE ______
METABOLISM
71
ToF the lower the activation energy the faster the reaction
T