Formative Histology Flashcards
where do you find the nuclei in skeletal muscles? [1]
is skeletal muscle uni or multicellular? [1]
where do you find the nuclei in skeletal muscles? [1]
pushed to the periphery
is skeletal muscle uni or multicellular? [1]
multicellular
where do you find in the nuceli in cardiac muscle? [1]
what makes cardiac muscles unique? [1]
where do you find in the nuceli in cardiac muscle? [1]
centrally located
what makes cardiac muscles unique? [1]
intercalated discs
when do you find skeletal muscle that has centrally located nuclei? [1]
when do you find skeletal muscle that has centrally located nuclei? [1]
when then muscle if regenerated after damage
what is a sarcomere? [1]
which lines does it lie between? [1]
what is a sarcomere? [1]
functional unit of muscle
which lines does it lie between? [1]
z disk to z disk
what is the Z line in sarcomere? [1]
what does it look like? [1]
what is the Z line in sarcomere? [1]
where the actin thin filament inserts: creates a dark band
what does it look like? [1]
dark line surroundered around pale section
what is the A band in sarcomere? [1]
what is the I band in sarcomere? [1]
what is the H zone in sarcomere? [1]
what is the M line? [1]
describe h
what is the A band in sarcomere? [1]
myosin filament - thick filament. some overlap with actin present
what is the M line? [1]
holds the myosin filament in place in sarcomere. no actin present
what is the I band in sarcomere? [1]
actin filament - thin filament
becomes darker on EM when the thick and thin overlap !
A: myosin & actin overlap
B: actin only
C: sarcomere
D: myosin only
E: I band
what is A & B?
what is the role of B [1]
A: mitochondria
B: t tubule
what is the role of B [1]
They allow transmission of the action potential, with its attendant ion shifts, to all parts of the cell, which allows rapid activation of the entire cell
what does this slide show?
what is M and T? [2]
myotendinous insertion:
M: muscle
T: tendon
where type of collagen is tendon? [1]
name for fibroblasts in tendons? [1]
where type of collagen is tendon? [1]
type 1 collagen
name for fibroblasts in tendons? [1]
tenocytes
what is the enthesis? [1]
what is the enthesis? [1]
bone / tendon insertion: tendon to fibrocartilage to calficified fibrocartilage
A & B?
A: osteoclasts
B: osteoblasts
why can you get an estimate of bone marrow by undertaking a bone biopsy? [1]
why can you get an estimate of bone marrow by undertaking a bone biopsy? [1]
as we age, get a transition from red bone marrow –> yellow bone marrow (adipocytes)
what is A?
A = secondary ossification centre
how does hyaline cartilage structure change superficial, middle and deep, for bone developemnt
- **collagen orientation
- proteoglycan content
- chondrocyte morphology**
at the epiphyseal growth plate:
