Final strength and conditioning Flashcards
Give an example of hormonal amplification?
Hypothalamus produces corticotropin releasing hormone (CRH) to the pituitary gland
Pituitary gland produces ACTH
ACTH stimulates the adrenal gland to produce cortisol. Cortisol levels help to control the pituitary’s production of ACTH
At each stage the production is amplified
The primary site of production, tissue/organs of action and major physiological functions of growth hormone?
Pituitary gland
Bone, muscle, connective tissue
Cell reproduction/regeneration, stimulate glycogenolysis and lipolysis
The primary site of production, tissue/organs of action and major physiological functions of oxytocin?
Pituitary gland
Uterus, breast tissue
Stimulates contraction during labour, stimulates contraction to produce milk
The primary site of production, tissue/organs of action and major physiological functions of leptin?
Adipose tissue
Hypothalamus
Suppression of appetite
The primary site of production, tissue/organs of action and major physiological functions of progesterone?
Ovaries
Female reproductive tract, breast tissue
Maintains structure, promotes sex characteristics
The primary site of production, tissue/organs of action and major physiological functions of atrial natriuretic hormone?
heart
Kidney
Stimulates excretion of urine
Importance of systemic changes in hormone delivery with exercise?
Fluid volume shifts:
More cellular water, less blood water = amplified endocrine effect from blood borne hormones
Blood flow re-distribution during exercise:
Greater amount of hormones delivered to working muscles
Increased cardiac output so quicker delivery to muscle tissue
Exercise can alter the concentration and sensitivity of receptors to their specified hormone
Acute effects of testosterone on muscle tissue?
Stimulates production of neurotransmitters increases force
Facilitates calcium release from sarcolemma increases force
Increases muscle protein synthesis
Acute GH response to exercise?
Exercise stimulates release (increased blood lactate)
Longer duration exercise causes more GH to be made (fuel mobilisation)
Concentration peaks after exercise (tissue repair role)
Only binds to muscle cells that have been active
What is hyperplasia?
Increase in the number of muscle fibres via longitudinal fibre splitting
What is hypertrophy?
Muscular enlargement from an increase in Cross sectional area of existing fibres
Occurs in parallel
However some exercise stimulate hypertrophy in series (lengthening), doesn’t increase force but increase velocity
Difference between sarcoplasmic hypertrophy and myofibrillar hypertrophy?
Myofibrillar is when growth occurs from increased amount of myofibrils eg actin and myosin
Sarcoplasmic hypertrophy is when the sarcoplasm of the muscle increases (force doesn’t really increase, however cell swelling leads to more muscle cell growth
How does hypertrophy work?
Satellite cells activate ad migrate to site from muscle damage
Duplicated and replicated
Donation of nuclei
Myoblasts turn into myotubes
Why does hypertrophy occur?
Mechanical tension - most important
Metabolic stress
Muscle damage
Does metabolic stress lead to?
Increased fibre recruitment
Elevated hormones
Altered myosin production
Accumulation of reactive oxygen species
Cellular swelling - stimulates PI3K