ANTI VIRUELNCE FINAL DECK Flashcards

1
Q

Johnson, 1991?

A

Virulence factors = ,Properties, products, structures, overcome, host defences, colonise or invade

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2
Q

Lenski, 1998?

A

Economic cost of antibiotics

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3
Q

Miller, 2001?

A

Quorum sensing, control, gene expression, fluctuations, cell population density, cause disease

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4
Q

Rasko, 2010?

A

Regulated, AHL’s, gene expression, virulence factors, biofilm formation

Interferring agents, agonis, inhibitors, AHL’s, Enzymes or antibodies

Prevent signal, prevent disease

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5
Q

Dong, 2005?

A

Quorum quenching, AHL degradtion enzymes, from bacteria, disable AHL

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6
Q

Lin, 2003?

A

Ralstonia SP, bacterium, gene cloned, for AHL deactivation, effective, in Escherichia Coli

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7
Q

Simoes, 2010?

A

Biofilms, extracellular, matrix, community, free swimming to surface attached, resistant phenotype, difficult to eradicate, foodbourne pathogen

Transport, planktonic cells, liquid to surface, adsorption of cells at surface, cell-cell signalling molecules produced, transport within biofilm

Substrate metabolism, cell growth, replication, EPS production

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8
Q

Lee, 2014?

A

Staphylococcus aureus, human pathogen, a toxin, haemolytic
Biofilm, aids virulence
Cis nerolidol, oil, plants, flowers, inhibited formation, then, haemolytic activity, then a-toxin gene hla
Hence anti virulent

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