Female Reproductive Pharmacology Flashcards
Estrogens
Treat symptoms of menopause (hot flashes, vaginal dryness, fatigue) through hormone replacement therapy (HRT).
Long term use has been linked to thrombophlebitis and breast and endometrial cancer
conjugated estrogens: Cenestin, Premarin
antifuingals
Treat Vaginal yeast infection by altering the yeast cell membrane or interfering with a metabolic process.
Most antifungals used to treat yeast infections are applied topically as ointments, suppositories, or vaginal tablets
miconazole: Monistat
nystatin: Mycostatin; Nilstat
Oral contraceptives
Prevent ovulation
oral contraceptives, or birth control pills contain a combination of estrogen and progestin and are highly effective in preventing pregnancy if taken as directed.
desogestrel/ethinyl estradiol: Desogen, Ortho-Cept
ethinyl estradiol/norgestrel: Lo/Ovral-28
oxytocics
Induce labor at term by increasing the strength and frequency of uterine contractions.
Oxytocics are also used during the postpartum period to control bleeding after the expulsion of the placenta.
oxytocin: Pitocin
prostaglandins
terminate pregnancy
Large doses of certain prostaglandins can cause the uterus to contract strongly enough to spontaneously abort a fetus
dinoprostone: Prostin E2, Cervedil
mifepristone: Mifeprex
spermicides
chemically destroy sperm by creating a highly acidic environment in the uterus
Spermicides are available in foam, jelly, gel and suppositories. They are used within the female vagina for contraception. Higher failure rate than other forms of contraception.
nonoxynol 9, octoxynol 9: Semicid, Koromex, Ortho-Gynol