Female Reproductive Flashcards
Menstrual cycle day 0-14
Follicular phase
Menstrual cycle day 14-28
Luteal phase
At low concentration what effect does estrogen have on LH
Negative feed back and this inhibits it’s release
At high concentration what effect does estrogen have on LH
Positive feedback
Spike in LH
And Lowers FSH
What does the follicle stimulating hormone do?
Facilitates maturation of a single ovum
When does LH spike and what does it mark
At 14 days and marks ovulation so release of oocyte from the follicle
What role does progesterone play in luteal phase
Progesterone will cause negative feedback on hypothalamus inhibiting GnRH
It will stimulate the growth of endometrial lining which will shed or the egg will implant
What does Y chromosome have?
Sex-determining region (SRY) gene which causes the gonads to differentiate into testes
Where is the ova or egg produced
In the follicles in the the ovaries
Every month…
An egg is ovulated in to the peritoneal sac and drawn into the Fallopian tube or oviduct
Oogonium
One haploid ovum and variable polar bodies
Primary oocytes
At birth all oogonia have already undergone replication and are arrested in prophase I
Secondary oocyte
Ovulated egg each month and arrested in metaphase II
Oocytes are surrounded by…
Zona pellucida and corona radiata
Zona pellucida
An acellular misfire of glycoproteins that protect the oocyte and contain necessary compounds for sperm binding
Corona radiata
Layer of cells that adhere to the oocyte during ovulation
Follicular phase
Usually lasts about 10 days Follicle-stimulating (FSH) hormone is released by the pituitary to begin ovulation FSH stimulates the follicle and ovum to mature Resulting in the release of Estrogen and preparation of the uterine lining
Ovulation has
The pituitary stops producing FSH and starts producing Luteinizing Hormone (LH) Now 3 Hormones - LH, estrogen, and FSH arecirculating within the female body. Estrogen + feedback At day 14 in the menstrual cycle, the follicle ruptures and the ovum is released (Ovulation)
Luteal phase
Secretes Progesterone and continues to do so if the egg is fertilized. High progesterone (-) feed back on GnRH, FSH and LH Prevents further ovulation and maintains the uterine lining Lasts about 14 days
Menstruation
When there is no fertilization and as estrogen and progesterone drop, endometrial lining sloughed off and the block of GnRH production removed
The corpus luteum diminishes
progesterone production
Pregnancy
Blastula produces human chorionic gonadotropin (hCG) which maintains sprouts luteum
Menopause
When ovaries stop producing estrogen and progesterone and stopes FSH and LH levels to rise
From birth to before ovulation all cells in
Prophase I and called primary oocytes
At ovulation cell completes
Meiosis I and arrested in metaphase II as haploid and called secondary oocyte. When sperm penetrates through secondary oocyte it’s completes meiosis II to mature ovum
Estrogen known cause of
Growth of endometrial lining in follicular phase
In males FSH stimulates
Sertoli cells and triggers spermatogenesis
In females FSH stimulates
Development of ovarian follicles
In males LH stimulates
Causes interstitial cells to produce tetosterone
In females LH stimulates
Causes ovulation and release of progesterone by corpus lumen