6 Different Classes Of Enzymes

Question 1

What are the 6 different classes of enzymes and how to remember them?

Answer 1

LI’L HOT

Ligase
Isomerase
Lyase
Hydrolase
Oxidoreductase
Transferase

Question 2

Ligase

Answer 2

Joining 2 large biomolecules, often the same one
Often required ATP
ex: synthetase

Question 3

Isomerase

Answer 3

Catalyzes the interconversion of isomers, including both constitutional isomers and stereoisomers

ex: fumarase, phosphohexose isomerase
- same chemical formula but different structure

Question 4

Lyase

Answer 4

Cleavage of a single molecule into two products, or synthesis of small organic molecules

• Without the addition of water or transfer of electrons
• ex: synthase

Question 5

Hydrolase

Answer 5

Breaking of a compound into two molecules using the addition of water
ex: lipases, pepsin, amylase, peptidase, nuclease (breaking biomolecules) (digestive enzymes)

Question 6

Oxidoreductase

Answer 6

Oxidation and reduction reactions which involves transfer of electrons
-ex: NAD+ to NADP
Dehydrogenase, reductase, oxidase

Question 7

Transferase

Answer 7

Movement of functions group from one molecule to another

ex: kinases, phosphatase