Feline

Question 1

Tissue from a cat. Morph and cause.

Answer 1

Subcutaneous and mesenteric steatitis. Vitamin E deficiency. Diet high in unstaurated fatty acids (fish) with no vitamin E supplementation.

Question 2

Name the disease.

Answer 2

Osteogenesis imperfecta. Affects Type I collagen. Can’t be rickets - that would be at the costochondral junctions.

Question 3

Tissue from a dog. Morph.

Answer 3

Cystic mucinous gall bladder hyperplasia. Common in older dogs and sheep.

Question 4

Tissue from a cat. Morph.

Answer 4

Multifocal acute renal infarct. Thrombi are in interlobar arteries. Look for veg. valvular endocarditis when mutlifocal renal infarcts.

Question 5

Tissue from a cat. Morph and cause.

Answer 5

Pyogranulomatous ventriculuitis and encephalitis with hydrocephalus. Most common cause of hydrocephalus in cats is acquired due to FIP (dry form) due to occlusion of the mesencephalic aqueduct that drains the third ventrilce into the fourth ventricle.

Question 6

Tissue from a cat. Morph and cause and another lesion.

Answer 6

Multifocal to coalescing necrotizing hepatitis. Gram negative sepsis with hot Gram negatives. Francisella tularensis. Yersinia. Salmonella. Ileum, mes LN, spleen then lymphatics then liver. Any of those would be another affected organ.

Question 7

Tissue from a cat. Morph.

Answer 7

Corneal sequestrum.

Question 8

Tissue from a cat. Morph and most likely cause.

Answer 8

Multifocal granulomatous encephalitis. Most likely from Cryptococcus neoformans in a cat. Associated with immunosuppressed animals. Cryptococcomas are those in the brain.

Question 9

Tissue from a cat. Morph? Cause?

Answer 9

Multiple cranial osteochondromas. In cats, this is associated with FeLV. Growth plate gets pinched off and gets left behind but still undergoes endochondral ossification. In dogs, not viral related.

Question 10

Morph. Name another affected site.

Answer 10

Plasmacytic pododermatitis. Associated lesions are plasma cell stomatitis Bilataterally symmetric! Bx is just plasma cells. Also might find glomerulonephritis from excess Ab-Ag complex precipitation.

Question 11

Tissue from a cat. Name the disease. What are the expected histologic lesions? Name a nematode that can induce this presentation.

Answer 11

Feline asthma. Smooth muscle and peribronchial gland hyperplasia. Eosinophils in airways. Aelurostrongylus abstrusus.

Question 12

Etiology?

Answer 12

Physaloptera. Causes catarrhal gastritis. One of the largest nematodes of domestic species.

Question 13

Most likely outcome?

Answer 13

glaucoma. Iridial melanomas don’t met (scleral melanomas do met to the liver!).

Question 14

Bilateral, symmetrical, crusted lesions on the face of the cat is what disease until proven otherwise?

A. Pemphigus folicaeous

B. Pemphigus vulgaris

C. Bullous pemphigoid

D. Superficial necrolytic dermatitis

Answer 14

A. Pemphigus foliaceous!!! hands down!

causes more superficial erosions, remember it is a superficial acantholytic pustular dermatosis

Pemphigus vulgaris is rare, rare and not superficial, it is suprabasilar clefting

Bullous pemphigoid is SUBepidermal clefting (bigger vesicles) and more common in horses and Yucatan minipigs

Superficial necrolytic dermatitis is hepatocutaneous syndrome, it is rare in cats and can be caused by pancreatic neoplasms like glucagonoma

Images from BMC 2020 review, and Dr. Weiner Davis-Thompson Foundation lecture Classic Skin Diseases and Hair Follicle Tumors