F - Acid-Base Interpretation - Karius Flashcards
If the respiratory system is compromised how will pH be brought back to normal?
Kidneys
-DCT/CD are about to secrete HCO3 or H+
If you are respiratory acidotic, what is released into blood and urine?
H+ into urine
HCO3 into blood
-this will increase plasma bicarbonate levels
If you are respiratory alkalotic, what is released into blood and urine?
HCO3 into urine
H+ into blood
-will decrease plasma bicarbonate levels
If metabolism is compromised and pH changes, what system will bring pH back to normal?
Respiratory system
- this will occur via chemoreceptors
- peripheral - aortic arch, carotid
If there is an increase in H+ in the blood (decreased pH) what will happen to ventilation and PaCO2?
Ventilation will increase to blow off more CO2
This will reduce PaCO2 and bring pH back up
If there is an decrease in H+ in the blood (increased pH) what will happen to ventilation and PaCO2?
Ventilation will decrease to retain more CO2. This will increase PaCO2 and bring pH back down
If respiratory disturbance what two things change?
CO2 and pH change in the opposite direction
If metabolic disturbance what two things change?
HCO3 and pH change in the same direction
What is the rule of thumb to determine if the problem is acute or chronic?
Look to the other system to answer the question
Acute respiratory acidosis equation
Expected HCO3 = 24 + (CO2 -40/10)
Chronic respiratory acidosis equation
Expected HCO3 = 24 + 4(CO2 - 40/10)
Metabolic acidosis equation
Expected CO2 = 1.5(HCO3) + 8+-2
What can change HCO3?
Kidneys -
GI tract - can lose HCO3 from V/D
Too many Tums
***Can use it up making acid you hadn’t planned to —> Lactic acid, ketoacids
Anion Gap equation
Na - Cl- - HCO3-
What is the normal anion gap?
< or equal to 12