Exam Three - Hypothalamus Flashcards
The ___ and __ control the endocrine system and the ANS to maintain homeostasis
hypothalamus
limbic system
what 3 things does the hypothalamus control
water balance
temperature
hunger
what ANS thing does the pons control
respiration
what 4 ANS things does the medulla control
respiration
cardiac
vomiting
swallowing
the nucleus of the solitary tract receives visceral info from these 3 cranial nerves
7, 9 ,10
the nucleus of the solitary tract relays info to the ___ nucleus which projects to the hypothalamus and other limbic structures
parabrachial
the facial, glossopharyngeal, and vagus nerves are all _____- CN with a ______ component
mixed
GVA
where does the solitary nucleus receive GVA input from?
- chemo/mechanoreceptors
- free endings of chemically and mechanically sensitive neurons
- minor input from nasal cavity, soft palate and sinus cavities
- gut wall, stretch of lungs, mucous membranes
what are some reflexes the solitary nucleus mediate
gag
carotid sinus
aortic
cough
baro/chemoreceptor
respiratory
GI system
output of the solitary nucleus
hypothalamus
amygdala
brainstem nuclei
what nucleus do the second order neurons project to in the hypothalamus
paraventricular
what nucleus do the second order neurons project to in the amygdala
central
what nuclei do the second order neurons project to in the brainstem
parabrachial
locus coeruleus
dorsal raphe
direct control of the autonomic preganglionic neurons arise from 4x
1 - hypothalamus
2 - parabrachial nucleus
3 - nucleus of solitary tract
4 - neurons in the ventrolateral medulla
indirect control of the autonomic responses originates from 3x
1 - cerebral cortex
2 - amygdala
3 - periaqueductal grey
what are humoral signals
BP and SCI
what 8 things does the hypothalamus do?
1 - control BP and electrolytes
2 - regulate body temp
3 - regulate energy metabolism
4 - regulate reproduction
5 - regulates circadian rhythms and sleep wake cycle
6 - directs responses to stress
7 - secretes trophic hormones
8 - interacts with limbic system to influence behavior and emotions
the hypothalamus lines the walls of this ventricle
3rd
what divides the hypothalamus into medial and lateral zones
fornix
what is a major input to the hypothalamus for sleep/wake cycle
retina
major inputs to hypothalamus
- orbitofrontal cortex
- brainstem and spinal cord
- hippocampus
- amygdala
major output of the hypothalamus
- orbitofrontal cortex
- septal nuclei
- adenohypophysis
- brainstem
- spinal cord
- anterior thalamic nucleus
- amygdala
what are the 3 regions of the hypothalamus
anterior
tuberal
posterior
What 2 nuclei make up the anterior region
1 - lateral and medial preoptic
2 - suprachiasmatic
what 6 nuclei make up the tubberal region
1 - paraventricular
2 - anterior nucleus
3 - supraoptic nucleus
4 - dorsomedial
6 - arcuate
what nuclei makes up the lateral posterior region
posterior area
mammillary body
mnemonic for the tuberal nuclei
seven
angry
vikings
ate
pink
donuts
seven
angry
vikings
ate
pink
donuts
1 - paraventricular
2 - anterior nucleus
3 - supraoptic nucleus
4 - dorsomedial
6 - arcuate
these nuclei regulate water balance and produce ADH and oxytocin
paraventricular
supraoptic
this nucleus regulates dissipation of heat and stimulates parasympathetic NS
anterior nucleus
this contains dimorphic nucleus and regulates release of gonadotrophic hormones
preoptic area
this receives input from retina and controls circadian rhythm
suprachiasmatic nucleus
stimulation of this nucleus results in obesity and savage behavior
dorsomedial
this regulates conservation of heat and stimulates sympathetic NS
posterior nucleus
stimulation of this nucleus induces eating and destruction of it causes starvation
lateral nucleus
this receives input from hippocampus formation via fornix and projects to the anterior nucleus of the thalamus. hemorrhagic lesion in wernickes encephalopathy
mammillary body
this is the satiety center and destruction of it leads to obesity and savage behavior
ventromedial nucleus
this produces hypothalamic releasing factors and contains DOPAergic neurons that inhibit prolactin release
arcuate nucleus
the lateral hypothalamus is the ____ center and ventromedial hypothalamus is the ___ center
feeding, satiety
the hypothalamus is sensitive to adiposity signals supplied by these 2 hormones
leptin and insulin
what secretes leptin
fat cells
these 3 hormones modulate neural activity in the arcuate nucleus of the hypothalamus
insulin
leptin
ghrelin
this is a satiety hormone while this is a hunger hormone
leptin
ghrelin
what 4 nuclei are involved in the sleep wake cycle
1 - lateral hypothalamic
2 - ventrolateral preoptic nucleus
3 - suprachiasmatic nucelus
4 - tubero-mammillary nucelus
this is responsible for controlling the circadian rhythm
suprachiasmatic nucleus
this is located within the posterior third of the hypothalamus, consists of largely histaminergic neurons and is involved in the control of arousal, learning, memory, sleep and energy balance
tuber-mammillary nucleus
what does the VLPO do?
inhibits the cholingergic nuclei and tuberomammillary nucleus which results in sleep
What do orexin neurons do
excite tubermammillary nucleus and raphe nuceli for wakefulness