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ORAL PATHOLOGY! > Exam 6-Salivary Tumors > Flashcards

Exam 6-Salivary Tumors Flashcards

1
Q

What % of salivary tumors affect the MAJOR glands? (therefore what % affects the minor glands?)

A

79% major (21% minor)

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2
Q

Which gland sees a vast majority of all salivary tumors?

A

the Parotid (69%)

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3
Q

Which is more prevalent: benign or malignant salivary tumors?

A

benign

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4
Q

Which gland actually has more of a predilection towards malignant tumors than benign?

A

the sublingual gland (70% malignant!)

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5
Q

IN THE MOST COMMON location for minor salivary gland tumors…THE PALATE…what are the chances it is benign or malignant?

A

about 1/2 and 1/2

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6
Q

Which two locations in the mouth show a LARGE predilection for maligant salivary tumors?

A

1.tongue (86% malignant) 2.Retromolar (90% malignant)

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7
Q

What are the only two regions of the mouth where we dont have salivary glands and therefore cannot get salivary tumors there?

A

gingiva or anterior dorsal tongue

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8
Q

Repeat concept: Salivary neoplasms are more common in ______ glands

A

major

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9
Q

Salivary neoplasms are more commonly benign or malignant?

A

benign

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10
Q

Minor gland tumors are more likely to be ________ than major gland disease

A

malignant

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11
Q

Minor gland neoplasms are most often in the WHICH REGION?? (be specific!)

A

post-lat hard palate

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12
Q

What is the MOST COMMON salivary neoplasm??

A

PleoMorphic adenoma

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13
Q

What is the MOST COMMON MALIGNANT salivary neoplasm?

A

MUCO-EPIDERMOID Carcinoma

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14
Q

What are the two Benign Salivary Tumors he pointed out for us to know? What is the official term for a benign salivary tumor?

A

Adenomas: pleomorphic adenoma (*most common) and ONCOcytoma (he didnt give any info on it)

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15
Q

What are the three types of benign salivary tumors that look like papillomas and where does each occur in the glandular system?

A

1.Sial-Adenoma Papilliferum (opening of duct) 2.IntraDuctal Papilloma (deep in the gland-lumen) 3.Inverted ductal papilloma (deepest in gland, grows down into connective tissue)

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16
Q

These are examples of what class of salivary tumor? Mucoepidermoid carcinoma, Adenoid cystic carcinoma, Polymorphous low grade adenocarcinoma (PLGA),Acinic cell carcinoma, Malignant mixed tumor

A

malignant (Adenocarcinomas)…

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17
Q

These are exampls of what class of salivary tumor? Are they rare or common? Basal cell adenocarcinoma, Epithelial-myoepithelial carcinoma, Salivary duct carcinoma, Myoepithelial carcinoma, Cystadenocarcinoma, Squamous cell carcinoma, Undifferentiated carcinoma

A

AdenoCarcinomas (rare) (except for SCC right?)

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18
Q

Clinical features of adenomas: Ulcerated or not?

A

usually without ulceration,

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19
Q

Clinical features of adenomas: slow or fast growth?

A

slow

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20
Q

Clinical features of adenomas: encapsulated or non-encapsulated?

A

encapsulated

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21
Q

Clinical features of adenomas: sessile or freely moveable?

A

freely moveable

22
Q

53-77% of PAROTID tumors are which kind?

A

Pleomorphic adenoma (most common tumor)

23
Q

Pleomorphic Adenomas are 44-68% of WHICH GLAND’s tumors?

A

submandibular

24
Q

Getting down to the nitty gritty-Pleomorphic adenoma: the _____ is the most common site for minor gland, upper lip, buccal mucosa

25
Q

Histologically, Pleomorphic Adenomas are a MIXTURE of _______ and _______ cells in myxoid ______ with areas of cartilage or bone

A

ductal and myoepithelial….stroma

26
Q

All we NEED to know about CANAL-icular Adenoma is that they occur 75% of the time in which area of the mouth and they affect which age group most often??

A

upper lip…older adults (greater than 60 y/o)

27
Q

What is the MOST COMMON tumor of the upper lip?

A

Canal-icular Adenoma

28
Q

What is the fancy name for an ONCOcytoma?

A

OXY-philic Adenoma

29
Q

What is the main cause of an ONCOcytoma? What is it probably a function of?

A

lack of oxygen…aging

30
Q

Since an oncocyte needs more oxygen, what does it fill with to compensate that need?

A

mitochondira!

31
Q

Where does an ONCOcytoma most commonly occur?

A

85-90% in parotid

32
Q

Where is a Warthin tumor most commonly found?

A

parotid (2nd most common of the parotid behind a parotid tumor lol)

33
Q

Which sex is affected more by Warthin Tumors? What is the other major predisposing factor?

A

Males…SMOKING

34
Q

Histologically, a Warthin Tumor is a cystic tumor lined by columnar ________ with lymphoid stroma

35
Q

What is the treatment for adenomas?

A

surgical, enucleated most the time easily removed

36
Q

Many of the adenocarcinomas are fairly ______ so they do not grow very rapidly and are not very aggressive (but there are exceptions)

37
Q

Two distinguishing factors that help us diagnose adenocarcinomas are that mucoeps may contain ______ spaces and present as ______ masses

A

cystic…BLUISH

38
Q

PEN AND PAPER: What are the 5 types of malignant adenocarciomas?

A

1.Muco-Epidermoid Carcinoma 2.Adenoid Cystic Carcinoma 3.Polymorphous low-grade adenocarcinoma (PLGA) 4.Acinic Cell Carcinoma 5.Malignant MIXED tumor

39
Q

What is the MOST COMMON malignant salivary neoplasm?

A

MUCO-epidermoid carcinoma

40
Q

A mucoepidermoid carcinoma is a tumor of _______ cells and _______ cells.

A

mucus…epidermoid lol

41
Q

What is the MOST COMMON malignant salivary gland tumors in CHILDREN???

A

MucoEpidermoid Carcinoma

42
Q

Which gland is most affected by mucoepidermoid carcinoma?

43
Q

MucoEpidermoid Carcinoma IS THE ONE salivary gland tumor that occurs CENTRALLY IN THE ______

44
Q

WHICH malignant salivary tumor is NO-TOR-IUS for its PERINEURAL invasion which grows away from the main tumor mass and results in recurrence locally?

A

Adenoid Cystic Carcinoma

45
Q

Adenoid Cyctic Carcinoma has a tendency for ________ invasion

A

perinural (when excised-nerve gets cut out)

46
Q

What is the prognosis for Adenoid Cystic Carcinoma short term and long term?

A

decent short term, poor long term

47
Q

Polymorphous Low Grade Adenocarcinoma is the ____ most common intraoral malignant salivary gland tumor

48
Q

What is the 2nd most common intraoral malignant salivary gland tumor? What is its prognosis?

A

Polymorphous Low Grade AdenoCarcinoma…good prognosis-hence “low grade”

49
Q

Where is an acinic cell carcinoma primarily located? What is the prognosis?

A

parotid…low grade

50
Q

Histologically, an acinic cell carcinoma will show a tumor of acinar cells, usually WHICH TYPE??

51
Q

SAY WHATTT? if you leave a pleomorphic adenoma a SMALL number of them will become malignant…what is the name of this tumor?

A

Malignant MIXED tumor

52
Q

What is a REG FLAG for a malignant MIXED tumor?

A

something that was slow growing, suddenly RAPIDLY progresses

ORAL PATHOLOGY! (40 decks)

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