Exam 3-Other Malignant Tumors Flashcards
Which type of carcinoma has a frequency that equals the amount of cases per year of ALL OTHER CANCERS COMBINED???
Basal Cell Carcinoma
Basal Cell Carcinoma is ___% of all skin cancers
80%
What % of people in the US develop skin cancer (not sure, but I think specific to Basal Cell)
1/5 (20%) of US Americans :)
What % of Basal Cell Carcinomas affect the sun exposed areas of the H&N? Do this type of cancer show up intra-orally?
90% of them…does not occur intra-orally
Basal Cell Carcinoma: low grade, slow growing, almost never ________
metastasize
BIG WORDS COMING UP!! Most common clinical form of Basal Cell Carcinoma - __________, central often cratered ulceration with ROLLED, raised borders with ________ (dilated) vessels
nodulo-ulcerative…. tel-angi-ectatic
The histologic features of Basal Cell Carcinoma are ______s of basaloid epithelial cells showing invasive growth
islands
What is the prognosis for Basal Cell Carcinoma? Survival rate after 5 years is ___-___%
90-95%
Still considered an epithelial cancer (carcinoma), What is the syndrome that arises from nasopharyngeal cancer that blocks the foramen ovale and therefore V3 causing referred jaw/tongue pain???
Trotter’s Syndrome
What is a “bulky or fleshy” mass under surface skin or mucosa?
A Sarcoma (mesenchymal)
About __% of H&N malignancies are sarcomas, affect broader age range
1%…EXCEEDINGLY RARE
What is a malignancy of fibrous connective tissue called?
A FibroSarcoma
What is a malignancy of fat? ….exceedingly rare in H&N
LipoSarcoma
What is a malignancy of vascular endothelium (general)? Where are a high number of these found?
AngioSarcoma…head and neck: scalp and forehead
What is a malignancy of vascular endothelium caused by HHV 8?
Kaposi’s Sarcoma (KS)
Kaposi’s Sarcmoma classically occurs in debilitated or __________ patients (HIV)
immunosuppressed
Kapok’s Sarcoma lesions can be _______, patch or mass lesion, usually reddish to ______
macular…purple
WOW, about ___% of HIV and KS patients present with oral lesions, they are found in which two areas of the mouth?
50%…gingival and hard palate
Which oral cancer can be palatally treated by intralesion Vinblastine, which causes the mass to necrose?
Kaposi’s Sarcoma
What is a malignancy of smooth muscle?
Leio-myo-sarcoma
What is a malignancy of skeletal muscle?
Rhabdo-myo-sarcoma
What is the MOST COMMON SOFT tissue malignancy in children?
Rhabdo-myo-sarcoma
What type of sarcoma presents as sarcoma BOT-RY-OIDES (grape like clusters off of surface mucosa)? Besides the head and neck, where is the most common location?
A RhabdoMyoSarcoma…urogenital tract
WOAH. A NeuroGenic Sarcoma is also called a: (get ready 5 word term)
Malignant peripheral nerve sheath tumor (neurogenic sarcoma)
A malignant peripheral nerve sheath tumor can arise in _________
neuro-fibro-matosis
What are the three typical treatments for a sarcoma?
surgery, radiation, chemo
The most common malignancy IN WHAT TISSUE is metastatic disease
bone
What fraction of metastatic malignancy migrates to bone? What hard tissue and soft tissue of the oral cavity will it most likely show up?
2/3….80%mandible, 20%maxilla…gingiva
For males, what are the 2 most common primary sites of cancer that then spread to the oral cavity?
1.Lung 2.Prostate
For females, what are the 2 most common primary sites of cancer that then spread to the oral cavity?
1.BREAST 2.Kidney
ATTENTION DENTISTS! apex ___% of diagnosis of metastatic caner in the oral cavity PRECEEDS the diagnosis of the primary cancer!!!!!!!
23%
Clinical manifestation of metastatic cancer in the mouth: pain, paresthesia, swelling, and LAST BUT NOT LEAST:
loosening of teeth
Radiographic findings of metastatic cancer is usually destructive, invasive, poorly marginated __________.
RADIOLUCENCY
Radiographic findings of metastatic cancer RARELY stimulates PRODUCTION of bone or osteosclerosis (classically from WHICH TYPE OF CANCER??????)
PROSTATE…FASCINATING!!!!
