Exam 3-Other Malignant Tumors

Question 1

Which type of carcinoma has a frequency that equals the amount of cases per year of ALL OTHER CANCERS COMBINED???

Answer 1

Basal Cell Carcinoma

Question 2

Basal Cell Carcinoma is ___% of all skin cancers

Answer 2

80%

Question 3

What % of people in the US develop skin cancer (not sure, but I think specific to Basal Cell)

Answer 3

1/5 (20%) of US Americans :)

Question 4

What % of Basal Cell Carcinomas affect the sun exposed areas of the H&N? Do this type of cancer show up intra-orally?

Answer 4

90% of them…does not occur intra-orally

Question 5

Basal Cell Carcinoma: low grade, slow growing, almost never ________

Answer 5

metastasize

Question 6

BIG WORDS COMING UP!! Most common clinical form of Basal Cell Carcinoma - __________, central often cratered ulceration with ROLLED, raised borders with ________ (dilated) vessels

Answer 6

nodulo-ulcerative…. tel-angi-ectatic

Question 7

The histologic features of Basal Cell Carcinoma are ______s of basaloid epithelial cells showing invasive growth

Answer 7

islands

Question 8

What is the prognosis for Basal Cell Carcinoma? Survival rate after 5 years is ___-___%

Answer 8

90-95%

Question 9

Still considered an epithelial cancer (carcinoma), What is the syndrome that arises from nasopharyngeal cancer that blocks the foramen ovale and therefore V3 causing referred jaw/tongue pain???

Answer 9

Trotter’s Syndrome

Question 10

What is a “bulky or fleshy” mass under surface skin or mucosa?

Answer 10

A Sarcoma (mesenchymal)

Question 11

About __% of H&N malignancies are sarcomas, affect broader age range

Answer 11

1%…EXCEEDINGLY RARE

Question 12

What is a malignancy of fibrous connective tissue called?

Answer 12

A FibroSarcoma

Question 13

What is a malignancy of fat? ….exceedingly rare in H&N

Answer 13

LipoSarcoma

Question 14

What is a malignancy of vascular endothelium (general)? Where are a high number of these found?

Answer 14

AngioSarcoma…head and neck: scalp and forehead

Question 15

What is a malignancy of vascular endothelium caused by HHV 8?

Answer 15

Kaposi’s Sarcoma (KS)

Question 16

Kaposi’s Sarcmoma classically occurs in debilitated or __________ patients (HIV)

Answer 16

immunosuppressed

Question 17

Kapok’s Sarcoma lesions can be _______, patch or mass lesion, usually reddish to ______

Answer 17

macular…purple

Question 18

WOW, about ___% of HIV and KS patients present with oral lesions, they are found in which two areas of the mouth?

Answer 18

50%…gingival and hard palate

Question 19

Which oral cancer can be palatally treated by intralesion Vinblastine, which causes the mass to necrose?

Answer 19

Kaposi’s Sarcoma

Question 20

What is a malignancy of smooth muscle?

Answer 20

Leio-myo-sarcoma

Question 21

What is a malignancy of skeletal muscle?

Answer 21

Rhabdo-myo-sarcoma

Question 22

What is the MOST COMMON SOFT tissue malignancy in children?

Answer 22

Rhabdo-myo-sarcoma

Question 23

What type of sarcoma presents as sarcoma BOT-RY-OIDES (grape like clusters off of surface mucosa)? Besides the head and neck, where is the most common location?

Answer 23

A RhabdoMyoSarcoma…urogenital tract

Question 24

WOAH. A NeuroGenic Sarcoma is also called a: (get ready 5 word term)

Answer 24

Malignant peripheral nerve sheath tumor (neurogenic sarcoma)

Question 25

A malignant peripheral nerve sheath tumor can arise in _________

Answer 25

neuro-fibro-matosis

Question 26

What are the three typical treatments for a sarcoma?

Answer 26

surgery, radiation, chemo

Question 27

The most common malignancy IN WHAT TISSUE is metastatic disease

Answer 27

bone

Question 28

What fraction of metastatic malignancy migrates to bone? What hard tissue and soft tissue of the oral cavity will it most likely show up?

Answer 28

2/3….80%mandible, 20%maxilla…gingiva

Question 29

For males, what are the 2 most common primary sites of cancer that then spread to the oral cavity?

Answer 29

1.Lung 2.Prostate

Question 30

For females, what are the 2 most common primary sites of cancer that then spread to the oral cavity?

Answer 30

1.BREAST 2.Kidney

Question 31

ATTENTION DENTISTS! apex ___% of diagnosis of metastatic caner in the oral cavity PRECEEDS the diagnosis of the primary cancer!!!!!!!

Answer 31

23%

Question 32

Clinical manifestation of metastatic cancer in the mouth: pain, paresthesia, swelling, and LAST BUT NOT LEAST:

Answer 32

loosening of teeth

Question 33

Radiographic findings of metastatic cancer is usually destructive, invasive, poorly marginated __________.

Answer 33

RADIOLUCENCY

Question 34

Radiographic findings of metastatic cancer RARELY stimulates PRODUCTION of bone or osteosclerosis (classically from WHICH TYPE OF CANCER??????)

Answer 34

PROSTATE…FASCINATING!!!!