Exam 6-LCH, ORN, TBC Flashcards

1
Q

What is the freaking CLASSIC sign of Langerhan’s Cell Histocytosis??

A

FLOATING TEETH

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2
Q

What are the two synonyms for Langerhan’s cell histocytosis?

A

Langerhan’s Cell Disease and HistioCytosis X

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3
Q

What age group is most affected by Langerhan’s cell histocytosis? 50% of patients are under WHAT AGE??

A

young patients (rare in adults)…50% under age 10

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4
Q

What two types of tissues are affected by Langerhan’s Cell Histocytosis?

A

bone and soft tissue

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5
Q

What are the three flavors of Langerhan’s cell Histocytosis? AND, PLEASE rank them in order of worst prognosis to best?

A

1.Letter-er-SI-WE Disease 2.Hand-SCHULER-Christian Disease 3.EiosinophiLIC Granuloma

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6
Q

Which flavor of Langerhan’s cell Histocytosis is also known as Acute Disseminated Langerhans Cell Histiocytosis?

A

Letterer-SI-WE disease

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7
Q

What age range is most affected by Letterer-SI-WE disease?

A

infants under 2 years

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8
Q

Which flavor of Langerhan’s cell Histocytosis involves multiple organs and sites, has an AGGRESIVE disease course and is invariably FATAL?

A

Letterer-SI-WE Disease

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9
Q

Letterer-SI-WE disease is also known as:

A

ACUTE Disseminated Langerhans Cell Histiocytosis

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10
Q

Hand-Schuler-Christian Disease is also known as:

A

CHRONIC Disseminated Langerhans Cell Histiocytosis

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11
Q

Chronic Disseminated Langerhans Cell Histiocytosis is also known as:

A

Hand-Schuler-Christian Disease

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12
Q

What is the typical age range for kids with Hand-Schuler-Christian disease?

A

3-10 years old

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13
Q

Which flavor of Langerhan’s cell Histocytosis has multiple sites of involvement, Slower progression with better prognosis?

A

hand-schuler-christian disease

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14
Q

Which flavor of Langerhan’s cell Histocytosis is also known as CHRONIC LOCALIZED Langerhans Cell Histiocytosis?

A

Eiosinophillic granuloma

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15
Q

Which age group is primarily affected by eiosinophillic granuloma?

A

teenagers and young adults

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16
Q

What is the main tissue type affected by eiosinophillic granuloma?

A

bone

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17
Q

What is the prognosis of eiosinophillic granuloma?

A

generally good

18
Q

Radiographic features of Langerhans Cell Histiocytosis: Radio______, singular/mulitple?, Often ill-defined; BUT may be ________

A

lucent…multiple, circumscribed

19
Q

Radiographic features of Langerhans Cell Histiocytosis: again, what is the CLASSIC radiographic sign???

A

“teeth floating in air”

20
Q

Radiographic features of Langerhans Cell Histiocytosis: The teeth are “floating in air” BUT they are NOT _______ by the lesion

A

displaced

21
Q

Radiographic features of Langerhans Cell Histiocytosis: what anatomical feature is typically lost (contributing to the “teeth floating in air” appearance)

A

loss of lamina dura

22
Q

What the heck ARE Langerhans Cells?? ________ cells involved in ______ processing

A

immune cells….antigen processing

23
Q

What are the two treatments for Langerhans Cell Histocytosis?

A

Curettage and/or low dose radiation therapy

24
Q

Freggin slam dunk: which condtion is always seen in an area of radiation therapy?

A

OsteoRadioNecrosis

25
Q

When seeing osteoradionecrosis of the jaw, the patient will give a history of prior cancer, usually ________

A

squamous cell carcinoma

26
Q

WHY does ORN happen? Radiation permanently damages the bone by destroying ________ in the area

A

blood vessles

27
Q

What is one of the major complications from OSN? Increases susceptibility to _______

A

INFECTION

28
Q

In ORN, The higher the ___________, the GREATER the risk

A

radiation dose

29
Q

In ORN, Severe ______ is INVARIABLY present

A

PAIN

30
Q

In ORN the lesion will NOT heal without _________

A

SURGICAL INTERVENTION

31
Q

What is the MOST IMPORTANT treatment for ORN??

A

PREVENTION

32
Q

For PRE-treating before radiation therapy, Extract ALL questionable teeth that will be in the ______ of radiation

A

field of radiation

33
Q

Once ORN is already present, treat by ________ regimen often used but efficacy questioned, ________ of dead bone to viable bleeding bone, _______ closure over the surgical site

A

Hyperbaric oxygen….resection…Soft tissue

34
Q

A traumatic bone cyst is also known as a _______

A

simple bone cyst

35
Q

Traumatic Bone Cyst (Simple bone cyst)–Clinical features: Radio_____ lesion, often ______ up between tooth roots

A

lucent…scallops

36
Q

Traumatic Bone Cyst (Simple bone cyst)–Clinical features: typically affects young patients who are active…so usually in their ____’s

A

20’s

37
Q

Traumatic Bone Cyst (Simple bone cyst)–Clinical features: they are __________, so they are often discovered by _______

A

Asymptomatic…radiographic exam

38
Q

Traumatic Bone Cyst (Simple bone cyst) Clinical features: which arch is affected? (almost EXLUSIVELY)

A

mandible

39
Q

Traumatic Bone Cyst (Simple bone cyst) Clinical features: are they expansile or non-expansile?

A

since there are no symptoms….non-expansile

40
Q

Traumatic Bone Cyst (Simple bone cyst) Clinical features: WHAT is discovered in the bone?? little/no ______ is recovered, or they contain _____ tinged fluid

A

an empty “hole”…tissue…blood

41
Q

WHICH pathology has characteristic “scalloping” up in between tooth roots?

A

Traumatic Bone Cyst (Simple bone cyst)

42
Q

How is a Traumatic Bone Cyst (simple bone cyst) typially treated?

A

STIMULATE BLEEDING and CURETTE