Exam 2 Slide show Muscle Tissue (Pt2) Flashcards

1
Q

Why are skeletal muscle fibers unable to undergo mitosis?

A

Because they are multinucleated (more than one nuclei)

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2
Q

During embryonic development, what fuses together to form one skeletal muscle fiber?

A

Myoblasts

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3
Q

What are able to regenerate functional muscle fibers to a limited degree by fusing with themselves or with damaged muscle fibers?

A

Satellite cells

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4
Q

Damaged skeletal muscle tissue typically undergoes ____ which is the replacement of muscle fibers by fibrous scar tissue

A

Fibrosis

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5
Q

The plasma membrane of a muscle fiber is termed what?

A

Sacrolemma

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6
Q

What is the cytoplasm of a muscle fiber

A

Sarcoplasm

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7
Q

What gives skeletal muscles its striated appearance?

A

Myofibrils

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8
Q

What is the Sarcoplasmic reticulum?

A

The smooth endoplasmic reticulum of a muscle fiber

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9
Q

What does the sarcoplasmic reticulum do?

A

Stores calcium ions, and releases them when the muscle fiber is stimulated

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10
Q

How do T-tubules open?

A

Like a cul-de-sac, only to the outside

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11
Q

What is is the calcium-binding protein inside the sarcoplasmic reticulum called?

A

Calsequestrin

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12
Q

Is the Ca++ concentration in a relaxed muscle less or higher than the cytosl?

A

higher, (10,000 times higher)

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13
Q

What are the dilated regions that flank the T-tubules?

A

Terminal cisterns

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14
Q

Two terminal cisterns flanking one T-tubule is called a

A

Triad

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15
Q

What are myofibrils made of?

A

Filaments

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16
Q

What are the two types of filaments?

A

Thick and Thin

17
Q

What are thin filaments composed of? What is their nature?

A

Actin: contractile protein

Troponin: regulatory protein

Tropomyosin: regulatory protein

18
Q

What are thick filaments composed of? What is their nature?

A

myosin; contractile protein

19
Q

What can be said about the ratio between thick and thin filaments?

A

there are two thin filaments for every thick filament

20
Q

What are the basic functional units of a myofibril?

A

Sarcomeres

21
Q

In the sarcomere, which band only has thin filaments?

22
Q

In the sarcomere, which zone only has thick filaments?

23
Q

In the sarcomere, which band has both thick and thin filaments?

24
Q

Muscle fiber proteins comprise of what three categories?

A

Contractile, Regulatory, and Structural proteins

25
Which proteins are considered contractile proteins?
Myosin and Actin
26
Which proteins are considered Regulatory proteins?
Troponin and Tropomyosin
27
Which proteins are considered structural proteins?
Titin, Myomesin, Dystrophin, and Sarcolemmal proteins