Embryology Flashcards

1
Q

name the 4 parts of the pharyngeal apparatus

A
  • pharyngeal arch
  • pharyngeal groove (cleft)
  • pharyngeal pouch
  • pharyngeal membrane
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2
Q

the pharyngeal arches are composed of ____ cells

A

neural crest

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3
Q

initially, pharyngeal arches have a core of ____ covered by ____ externally and ____ internally

A
  • mesenchyme
  • ectoderm
  • endoderm
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4
Q

name the components of the pharyngeal arches

A
  • artery
  • bone (cartilaginous rod)
  • muscle
  • nerve
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5
Q

the artery component of pharyngeal arches is derived from ____

A

truncus arteriosus

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6
Q

which pharyngeal arches develop separately?

A

1, 2, 3

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7
Q

the cartilaginous portion of pharyngeal arches ____ and ____ fuse

A

4 and 6

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8
Q

pharyngeal arch ____ regresses and has no derivatives

A

5

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9
Q

what structures develop from the frontonasal prominence?

A
  • optic vesicles (eyes)
  • forehead
  • stomodeum (primordial mouth)
  • nose (frontal & lateral nasal prominence)
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10
Q

meckel’s cartilage is associated with which pharyngeal arch?

A

1st

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11
Q

the first pharyngeal arch is also called the ____

A

mandibular arch

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12
Q

the bone/cartilage component of the first pharyngeal arch is also called ____

A

meckel’s cartilage

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13
Q

what structures develop from the bone/cartilage component of the first pharyngeal arch?

A
  • maxillary prominence
  • mandibular prominence
  • dorsal end (malleus, incus, sphenomandibular lig)
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14
Q

what muscles develop from the first pharyngeal arch?

A
  • mm of mastication
  • tensor veli palatini
  • tensor tympani
  • mylohyoid
  • ant. belly of digastric
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15
Q

which nerve develops from the first pharyngeal arch?

A

CN V : trigeminal

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16
Q

the second pharyngeal arch is also called the ____

A

hyoid arch

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17
Q

the bone/cartilage component of the second pharyngeal arch is called ____

A

Reichert’s cartilage

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18
Q

what bones/cartilage develop from the second pharyngeal arch?

A
  • stapes
  • styloid process
  • stylohyoid lig
  • lesser cornu & upper part of body of hyoid
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19
Q

what muscles develop from the second pharyngeal arch?

A
  • mm of facial expression
  • stapedius
  • stylohyoid
  • post. belly of digastric
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20
Q

what nerve develops from the second pharyngeal arch?

A

CN VII: facial

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21
Q

what is a branchial cyst?

A

persistent second pharyngeal groove or cervical sinus, apparent beginning in late childhood or early adulthood

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22
Q

what is the clinical presentation of a branchial cyst?

A
  • painless swollen mass
  • slowly enlarges
  • inferior to angle of mandible and anterior to SCM
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23
Q

which pharyngeal arch does NOT develop into adult structures?

A

5

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24
Q

what bones/cartilage develop from the third pharyngeal arch?

A
  • thyroid cartilage
  • hyoid bone (greater cornu & part of body)
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25
what muscle develops from the third pharyngeal arch?
stylopharyngeus
26
what nerve develops from the third pharyngeal arch?
CN IX: glossopharyngeal
27
what structures develop from the bone/cartilage component of the 4th and 6th pharyngeal arches?
laryngeal cartilages (except epiglottis)
28
what muscles develop from the 4th and 6th pharyngeal arches?
pharyngeal & laryngeal mm (cricothyroid, levator palatini, pharyngeal constrictors)
29
what nerve develops from the 4th and 6th pharyngeal arches?
CN X: vagus - 4th: sup. laryngeal n - 6th: recurrent laryngeal n
30
what structures develop in the first pharyngeal pouch region?
- tympanic cavity - mastoid antrum - pharyngotympanic (eustachian; auditory) tube - tympanic membrane
31
what structures develop in the second pharyngeal pouch region?
tonsillar fossa & palatine tonsils
32
what structures develop in the third pharyngeal pouch region?
- inferior parathyroid glands - thymus
33
what structures develop in the fourth pharyngeal pouch region?
- superior parathyroid glands - thyroid parafollicular cells
34
what structure develops in the first pharyngeal groove region?
external auditory meatus
35
what pharyngeal grooves lie in the cervical sinus and are obliterated as the neck develops?
all but 1st groove (if not, branchial cyst forms)
36
median and lateral lingual swellings develop from which pharyngeal arch?
1st
37
what tongue structure develops from the hypopharyngeal eminence?
rostral tongue
38
the hypopharyngeal eminence is a derivative of which pharyngeal arch?
4th
39
what nerve innervates the tongue during development?
CN XII: hypoglossal
40
when do taste buds develop?
weeks 11-13
41
what is the general timeline for facial development?
weeks 4-8 primary growth
42
what occurs by week 5 of facial development?
- primordial auricles (ears) begin developing - ears migrate up from neck region as mandible develops
43
what occurs by week 6 of facial development?
- maxillary & lateral nasal prominence begin fusion at nasolacrimal duct - oronasal membrane ruptures
44
what occurs by week 12 of facial development?
conchae and olfactory epithelium develop
45
when do air sinuses develop?
- maxillary sinuses: fetal development - other air sinuses: after birth
46
what causes a chin dimple?
incomplete fusion of left and right mandibular prominences
47
when does development of the palate begin?
week 6
48
what 2 portions of the palate develop by week 6?
- primary palate: premaxillary part of maxillae - secondary palate: lateral palatine processes (palatine shelf)
49
prevalence of cleft lip
- 1 in 1000 births - M>F (60-80% boys)
50
prevalence of cleft palate
- 1 in 2500 births - F>M
51
describe the development of the retina and ciliary body
- optic vesicles project from forebrain - invaginates to form optic cups - develops into retina & ciliary body
52
describe the development of the lens
- surface ectoderm forms lens placode - develops into lens
53
describe the development of the inner ear
- surface ectoderm thickens into otic placode - invaginates to form otic pit - edges of pit fuse to form otic vesicle -> forms inner ear
54
the middle ear (ossicles and auditory tube) develop from which pharyngeal arches?
1st & 2nd
55
the external ear develops from the ___ and ___ pharyngeal arches, and the ___ pharyngeal groove
- 1st & 2nd arches - 1st groove
56
what is the first endocrine gland to develop?
thyroid gland
57
what occurs by 24 days of thyroid gland development?
- thyroid primordium on back of tongue/pharynx - descends to neck through thyroglossal duct
58
what occurs by week 7 of thyroid gland development?
- thyroid gland assumes adult shape - reaches final site in anterior midline of neck - thyroglossal duct degenerates
59
what remnants of embryonical thyroid gland development may be present in adulthood?
- proximal opening of thyroglossal duct persists as foramen cecum on tongue - persistent thyroglossal duct (round firm mass/swelling in median plane of neck inf to hyoid bone)
60
A patient is born without a thymus gland and inferior parathyroid glands. Which portion of the pharyngeal apparatus is involved in this defect?
3rd pouch
61
Treacher-Collins syndrome is characterized by malformed or absent ears, zygomatic and mandibular hypoplasia and downward slanted eyes. This condition involves which pharyngeal arch?
1st pharyngeal arch
62
A 16-year-old female notices asymmetry in her neck when she tenses the skin of her inferior face and neck - she is lacking a platysma on one side of her neck. This asymmetry involves which pharyngeal arch?
2nd pharyngeal arch