Abdominal Embryology & Pathology Flashcards

1
Q

the primordial gut forms in week ____

A

4

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2
Q

what forms the primitive gut tube?

A

cephalocaudal and lateral folding

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3
Q

the primitive gut tube is bound cephalically by the ____ and caudally by the ____

A
  • oropharyngeal membrane
  • cloacal membrane
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4
Q

the midgut remains temporarily connected to what embryological structure during development?

A

yolk sac

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5
Q

the ventral mesentery is derived from…

A

mesenchyme of septum transversum

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6
Q

the dorsal mesentery is a continuous sheet extending along the posterior abdominal wall from the ____ to the ____

A

abdominal esophagus to rectum

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7
Q

what is the name for the early diaphragm?

A

septum transversum

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8
Q

name the structures of the foregut

A
  • primordial pharynx & derivatives
  • lower respiratory system
  • esophagus & stomach
  • duodenum (proximal to bile duct opening)
  • liver, biliary system (hepatic ducts, gallbladder, bile duct)
  • pancreas
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9
Q

what 2 foregut structures are derived from ventral mesogastrum?

A

lesser omentum
falciform ligament

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10
Q

the greater omentum is derived from ____

A

dorsal mesogastrum

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11
Q

what happens to the stomach during development?

A

clockwise rotation (90*) on longitudinal axis, forming omental bursa
- cardia portion moves left + downward
- pyloric portion moves right + upward

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12
Q

the dorsal mesogastrum fuses with the ____

A

transverse mesocolon mesentery

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13
Q

what forms the duodenal C-shape during development?

A

stomach rotation

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14
Q

what pushes the duodenum to the right of the midline?

A

pancreas grows concurrently

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15
Q

the liver develops as cells start to proliferate within portions of mesoderm derived from ____

A

septum transversum

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16
Q

what forms the bare area of the liver?

A

as liver grows, contacts central tendon of diaphragm

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17
Q

name the structures of the midgut

A
  • small intestine (includes duodenum distal to bile duct opening)
  • cecum
  • appendix
  • ascending colon
  • transverse colon (right 1/2 to 2/3)
18
Q

most midgut structures receive what arterial supply?

19
Q

what happens to the primary intestinal loop from ~weeks 5-7 of development?

A

rapid elongation of gut and mesentery

20
Q

what allows space for midgut rotation during development?

A

physiological umbilical herniation during week 8

21
Q

how does the midgut rotate during development?

A

270 degrees counterclockwise around SMA axis

22
Q

what happens after midgut rotation during development?

A

umbilical herniation retraction during week 10

23
Q

name the structures of the hindgut

A
  • transverse colon (left 1/3 to 1/2
  • descending colon
  • sigmoid colon
  • rectum
  • anal canal (sup. portion)
  • internal lining of bladder & urethra
24
Q

during development, the anal canal migrates into the ____

A

cloacal region

25
during development, the cloacal membrane ____
degenerates
26
the superior anal canal is derived from ____
endoderm (columnar epithelium)
27
the inferior anal canal is derived from ____
ectoderm (stratified squamous epithelium)
28
the pectinate line separates...
- superior anal canal - inferior anal canal (change from columnar to stratified squamous)
29
what 2 pouches form in the hindgut during development?
urorectal & rectovaginal
30
liver cirrhosis has a ____ external appearance
hobnail (rough/bumpy)
31
gallstones are also called ____
cholelithiasis
32
gallstones are made up of ____
cholesterol crystals
33
gallstones occur more in ____ and ____
females and older individuals (^risk w age)
34
gallstones can cause injury to the ____ or ____
gallbladder biliary tract obstruction
35
name 5 congenital renal anomalies
- ectopic kidneys - bifid renal pelvis or ureter - accessory renal aa - polycystic kidney disease - fused kidneys
36
multiple kidney stones are referred to as ____
renal calculi (mineral deposits)
37
name 2 hepatic pathologies
- cirrhosis - portal vein hypertension
38
kidney stone pain refers to...
lumbar (flank), inguinal region or external genetalia
39
what is renal colic?
severe intermittent pain as kidney stones pass through ureters
40
what can increase pain associated with pararenal inflammation and why?
extension of hip, due to relationship with psoas minor (lies directly behind ureter, shares some nerve supply)