Drugs💘 Flashcards
1
Q
Ec50
A
Concentration of drug which produces half maximal response
2
Q
Agonist
A
Drug which produces positive effect on receptor
3
Q
Antagonist
A
Drug which reduces effect of agonist
4
Q
Inverse agonist
A
Drug which has opposite effect to agonist
5
Q
The three gpcr subtypes
A
Rhodopsin family
Secretin/glucagon family
Calcium sensor family
6
Q
Short term tolerance
A
Tachyphylaxis is a reduced biological response to a drug to repeated prescriptions
7
Q
Long term tolerance
A
Over time it becomes drug tolerance and u need higher doses of the drug
8
Q
Dissociation constant
A
The concentration at which half of the drug is bound to the receptor at equilibrium
9
Q
Potency
A
The dose of a drug required to produce a specific effect at a given intensity
