Diseases of Head and Neck - skin and soft tissue pathology Flashcards

1
Q

What is the 6th most common cancer worldwide?

A

Oral Squamous Cell Carcinoma

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2
Q

What are the risk factors of oral cavity carcinoma?

A
  • tobacco
  • alcohol
  • Diet
  • Fam history
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3
Q

What is a viral cause of oral cavity carcinoma?

A

HPV

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4
Q

what strain of HPV causes carcinoma of the oral cavity?

A

HPV 16 and 18

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5
Q

What foods are risk factors of oral cavity carcinoma?

A

Meat and red chilli powder

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6
Q

What foods are protective againsts oral neoplasia?

A

foods high in vitamins A and C

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7
Q

Name some pre-cancerous lesions and conditons that can lead to oral carcinoma.

A

1) Submucous fibrosis
2) Actinic keratosis
3) Lichen Planus
4) Leukoplakia and erythroplakia
5) Chronic hyperplastic candidosis

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8
Q

What is Lichen Planus?

A

Lichen planus (LP) is a disease of the skin and/or mucous membranes that resembles lichen. (thought to be autoimmune)

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9
Q

what is leukoplakia?

A

areas of keratosis appear as firmly attached white patches on the mucous membranes of the oral cavity,

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10
Q

What is erythroplakia?

A

red patched on mucous membrane

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11
Q

what is chronic hyperplastic candidosis?

A

variant of oral candidosis that appears as a whit patch on mucous membranes.

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12
Q

What strains of HPV cause laryngeal carcinoma?

A

6 and 11

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13
Q

what type of cancer are metal and plastic workers at a higher risk of getting?

A

carcinoma of the larynx

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14
Q

What condition is associated with cutaneous lesions that are itchy, purple, papules forming plaques with wickham’s striae?

A

Lichen Planus

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15
Q

what condition is associated with oral lesions that are reticular striations, plaque like, erosive, ulcerative lesions and also associated with desquamative gingivitis?

A

Lichen Planus

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16
Q

What is most commonly associated with voice change such as hoarseness?

A

Vocal nodules and polyps

17
Q

Recurrent attacks of rhinitis can eventually lead to this condition . .

A

Nasal polyps

18
Q

What can arise from an extension of a periapical infection from an upper tooth through the antral floor?

A

Maxillary Sinusitis

19
Q

What are the potential complications of sinusitis?

A

potential of spread into the orbit or into the bone leading to cranial osteomyelitis. Also meningitis or cerebral abscesses.

20
Q

What is otitis media?

A

middle ear infection.

21
Q

What is the cause of acute otitis media?

A

Acute is often from bacterial infections caused by strep pneumoniae, H.Influenza, Moraxella Catarrhalis.

22
Q

What is the cause of chronic otitis media?

A
  • Pseudomonas aeruginosa

- Staphylococcus aureus

23
Q

What is cholesteatoma?

A

chronic inflammation and perforation of the eardrum caused by ingrowth of the squamous epithelium.

24
Q

What is Otosclerosis/

A

abnormal bone deposition in the middle ear.

usually bilateral

25
Q

What is labyrinthitis?

A

Inflammatory disorder of the inner ear or labyrinth.

can be due to an bacteria / viral or autoimmune process such as wegener ganulomatosis or polyarteritis nodosa.

26
Q

What condition of the external ear (pinna) is associated with actinic radiation and tends to occur in elderly men?

A

Basal cell and sqaumous cell carcinoma

27
Q

what are paragangliomas?

A

mos common tumour of the middle ear that originates in the paraganglia.

28
Q

What tumour are the following symptoms associated with?

  • pulsatile tinnitus
  • hearing loss
  • aural pressure
  • dizziness
  • otalgia
  • bloody otorrhea
A

Paragangliomas