Diseases of Head and Neck - skin and soft tissue pathology Flashcards
What is the 6th most common cancer worldwide?
Oral Squamous Cell Carcinoma
What are the risk factors of oral cavity carcinoma?
- tobacco
- alcohol
- Diet
- Fam history
What is a viral cause of oral cavity carcinoma?
HPV
what strain of HPV causes carcinoma of the oral cavity?
HPV 16 and 18
What foods are risk factors of oral cavity carcinoma?
Meat and red chilli powder
What foods are protective againsts oral neoplasia?
foods high in vitamins A and C
Name some pre-cancerous lesions and conditons that can lead to oral carcinoma.
1) Submucous fibrosis
2) Actinic keratosis
3) Lichen Planus
4) Leukoplakia and erythroplakia
5) Chronic hyperplastic candidosis
What is Lichen Planus?
Lichen planus (LP) is a disease of the skin and/or mucous membranes that resembles lichen. (thought to be autoimmune)
what is leukoplakia?
areas of keratosis appear as firmly attached white patches on the mucous membranes of the oral cavity,
What is erythroplakia?
red patched on mucous membrane
what is chronic hyperplastic candidosis?
variant of oral candidosis that appears as a whit patch on mucous membranes.
What strains of HPV cause laryngeal carcinoma?
6 and 11
what type of cancer are metal and plastic workers at a higher risk of getting?
carcinoma of the larynx
What condition is associated with cutaneous lesions that are itchy, purple, papules forming plaques with wickham’s striae?
Lichen Planus
what condition is associated with oral lesions that are reticular striations, plaque like, erosive, ulcerative lesions and also associated with desquamative gingivitis?
Lichen Planus
What is most commonly associated with voice change such as hoarseness?
Vocal nodules and polyps
Recurrent attacks of rhinitis can eventually lead to this condition . .
Nasal polyps
What can arise from an extension of a periapical infection from an upper tooth through the antral floor?
Maxillary Sinusitis
What are the potential complications of sinusitis?
potential of spread into the orbit or into the bone leading to cranial osteomyelitis. Also meningitis or cerebral abscesses.
What is otitis media?
middle ear infection.
What is the cause of acute otitis media?
Acute is often from bacterial infections caused by strep pneumoniae, H.Influenza, Moraxella Catarrhalis.
What is the cause of chronic otitis media?
- Pseudomonas aeruginosa
- Staphylococcus aureus
What is cholesteatoma?
chronic inflammation and perforation of the eardrum caused by ingrowth of the squamous epithelium.
What is Otosclerosis/
abnormal bone deposition in the middle ear.
usually bilateral
What is labyrinthitis?
Inflammatory disorder of the inner ear or labyrinth.
can be due to an bacteria / viral or autoimmune process such as wegener ganulomatosis or polyarteritis nodosa.
What condition of the external ear (pinna) is associated with actinic radiation and tends to occur in elderly men?
Basal cell and sqaumous cell carcinoma
what are paragangliomas?
mos common tumour of the middle ear that originates in the paraganglia.
What tumour are the following symptoms associated with?
- pulsatile tinnitus
- hearing loss
- aural pressure
- dizziness
- otalgia
- bloody otorrhea
Paragangliomas