Dextrose 50% (D50W, 50% Glucose)

Question 1

D50 - Class

Answer 1

Carbohydrate

Question 2

D50 - Actions

Answer 2

• Provides sugar for rapid absorption into the bloodstream

* Principle energy source utilized by the brain and other tissues

Question 3

D50 - Indications

Answer 3

• Suspected hypoglycemia with a glucometer reading of <60
• Suspected hypoglycemia when unable to obtain glucometer reading
• Suspected hyperkalemia in hemodialysis pt (widened QRS, peaked T waves, bradycardia)

Question 4

D50 - Dosage/Route

Answer 4

• Hypoglycemia or suspected hypoglycemia:
• 25 grams slow IVP (50 ml of 50% solution)
• May repeat if repeat glucometer remains <60
• Suspected hyperkalemia:
• 25 grams slow IVP (50 ml of 50% solution)

Question 5

D50 - Side Effects

Answer 5

Reduced serum potassium

Question 6

D50 - Contraindications

Answer 6

None in the emergency setting

Question 7

D50 - Special Information

Answer 7

• Onset of action 1 -2 min
• Determine glucometer reading prior to administration possible
• Tissue necrosis occurs with infiltration: ensure that the injection is IV; aspirate before and halfway through admin
• Assess effectiveness of admin with pt assessment

Question 8

D50 - Pediatric Note

Answer 8

• Refer to pediatric drug guide
• Under 3 yrs of age and <15 kg
• use dextrose 25% preload or dilute D50 1:1 with NS slow IVP