Cotrimoxazole Flashcards

1
Q

Composition ?

A

Sulfaméthoxazole + synergie avec Triméthoprime (inhib dihydrofolate réductase microbienne)

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2
Q

Activité ?

A
E coli
Pneumocoque
NOCARDIA
Listéria
Staph aureus
Pneumocystose
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3
Q

EI ?

A
Hypersensibilité
Toxicité (anorexie / nausées / vomissement) 
-> ANEMIE HÉMOLYTIQUE (G6PD)
-> cytolyse hépatique
-> atteinte neuro
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4
Q

Seule indication de sulfafurazole + erythromycine ?

A

OMA allergique enfant (CI si inf à 2mois)

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