common brain lesions Flashcards

1
Q

common brain lesion - amygdala (bilateral) - manifestations

A

Kluver - Bucy syndrome –> disinhibited behavior:

  1. hyperphagia
  2. hypersexuality
  3. hyperpolarity
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2
Q

Kluver - Bucy syndrome - area of lesion and cause

A
  • amygdala (bilateral)

- HSV-1

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3
Q

common brain lesion - frontal lobe - manifestations

A
  1. Disinhibition
  2. deficits in concentration, orientation and judgement
  3. maybe re-emergence of primitive reflexes
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4
Q

common brain lesion - dominant parietal-temporal cortex

A

GERSTMANN SYNDROME

  1. Agraphia 2. acalculia 3. finger agnosia
  2. left - right disorientation
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5
Q

GERSTMANN SYNDROME is caused by

A

dominant parietal-temporal cortex lesion

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6
Q

acalculia

A

acquired impairment in which patients have difficulty performing simple mathematical tasks

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7
Q

agraphia

A

acquired neurological disorder causing a loss in the ability to communicate through writing

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8
Q

finger agnosia

A

inability to distinguish the fingers on the hand

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9
Q

common brain lesion - nondominant parietal-temporal cortex

A

Hemispatial neglect syndrome –> agnosia of the contralateral side of the world

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10
Q

Hemispatial neglect syndrome –>

A

agnosia of the contralateral side of the world

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11
Q

reticular activating system - area

A

midbrain

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12
Q

common brain lesions - reticular activating system - manifestations

A

reduced levels of arousal and wakefulness (eg. coma)

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13
Q

common brain lesions - frontal eye fields - manifestations

A

Eyes look torward lesion

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14
Q

common brain lesions - paramedian pontine reticular formation - manifestations

A

eyes look away from side of lesion

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15
Q

common brain lesions - hippocampus (bilateral) - manifestation

A

anterograde amnesia: inability to make new memories

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16
Q

common brain lesions - subthalamic lesion - manifestations

A

contralateral hemiballismus: sudden, wild flailing of 1 arm +/- ipsilateral leg

17
Q

common brain lesions - basal ganglia - manifestations

A

tremor at rest
chorea
athetosis

18
Q

common brain lesions - basal ganglia - disease?

A
  1. Parkinson disease

2. Huntington disease

19
Q

common brain lesions - cerebellar vermis - manifestations

A

truncal ataxia

dysarthria

20
Q

common brain lesions - Mamillary bodies (bilateral) - manifestations

A

Wernicke - Korsakoff syndrome: 1. confusion 2. ataxia

  1. ophthalmoplegia 4. memory loss 5. comfabulation
  2. personality changes
21
Q

Wernicke - Korsakoff syndrome - memory loss

A

anterograde and retrograde

22
Q

retrograde memory loss

A

loss of memory-access to events that occurred, or information that was learned

23
Q

Wernicke - Korsakoff syndrome is associated with

A

thiamine (B1) deficiency and excessive alcohol use

24
Q

Mamillary bodies (bilateral) / Wernicke - Korsakoff syndrome can be precipitated by

A

giving glucose without B1 to a B1-deficient patient

25
Q

common brain lesions - cerebellar hemisphere - manifestations

A

at the site of damage:

  1. intention tremor 2. limb ataxia
  2. loss of balance 4. fall toward side of lesion
26
Q

Gesrtman syndrome - common brain lesions?

A

Dominant parietal-temporal cortex

27
Q

disinhibition - common brain lesions?

A
  1. bilateral amygdala (Kluver-Bucy syndrome)

2. Frontal lobe

28
Q

common brain lesions - frontal eye field vs paramedian pontine reticular formation - according manifestations

A

frontal eye field –> eyes look toward lesion

paramedian pontine reticular formation –> eyes look away from the side of lesion

29
Q

frontal eye fields - location

A

in the frontal cortex

30
Q

frontal eye fields is responsible for

A

non-tracking, voluntary eye movements

31
Q

Cerebral hemisphere degeneration is associated with

A

chronic alcohol use