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neurology FA > CNS neurotransmitters > Flashcards

CNS neurotransmitters Flashcards

1
Q

CNS neurotransmitters - types

A
  1. Norepinephrine 2. Dopamine 3. 5-HT

4. ach 5. GABA

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2
Q

norepinephrine - change in disease

A

increased in anxiety

decreased in depression

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3
Q

norepinephrine - location of synthesis in CNS

A

Locus ceruleus (pons)

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4
Q

Dopomine - change in disease

A

increased in Huntington
decreased in Parkinson
decreased in depression
increased in Schizophrenia

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5
Q

Dopamine - location of synthesis in CNS

A

ventral tegmentum AND substantia nigra pars compacta (midbrain)

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6
Q

5-HT - change in disease

A

Decreased in anxiety
decreased in depression
INCREASED IN PARKINSON

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7
Q

5-HT - location of synthesis

A

Raphe nuclei (pons, medulla, midbrain)

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8
Q

ACH - change in diseases

A

increased in Parkinson
decreased in Alzheimer
decreased in Huntington

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9
Q

ACH - location of synthesis in CNS

A

Basal nucleus of Meynert

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10
Q

GABA - change in disease

A

decreased in anxiety

decreased in Huntington

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11
Q

GABA -location of synthesis in CNS

A

Nucleus accumbens

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12
Q

Locus ceruleus synthesize … and is responsible for

A

norepinephrine

stress and panic

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13
Q

reward center consits of

A

Nucleus accumbens and septal nucleus

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14
Q

reward center is responsible for

A

pleasure, fear, addiction

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15
Q

substances that stimulate reward center (and action)

A

endocannabinoids –> increase desire for high-fat foods

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16
Q

anxiety - changes in neurotransmitters

A

increased norepinephrine

decreased 5-HT and GABA

17
Q

depression - changes in neurotransmitters

A

decreased norepinephrine, dopamine and 5-HT

18
Q

Huntington disease -changes in neurotransmitters

A

decreased GABA, ACH

increased dopamine

19
Q

Parkinson disease - changes in neurotransmitters

A

decreased dopamine
increased ACH
INCREASED SERETONIN

20
Q

Alzheimer disease - changes in neurotransmitters

A

decreased ACH

increased glutamate

21
Q

locus coeruleus is a …. (area and function)

A

nucleus in the pons involved with physiological responses to stress and panic.
(υπομέλαν τόπος)

22
Q

Schizophrenia - changes in neurotransmitters

A

increased dopamine

23
Q

CNS neurotransmitters - types and location of synthesis

A
  1. Norepinephrine –> Locus ceruleus
  2. Dopamine –> Ventral tegmentum, substantia nigra pars compacta (midbrain)
  3. 5-HT –> Raphe nucleis
  4. ach –> Basal nucleus of Meynert
  5. GABA –> Nucleus accumbens

neurology FA (31 decks)

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