Chemical Coordination: Endocrine System Flashcards
second great integrative system that controls an animal’s activities and communicates through chemical messengers known as hormones.
Endocrine system
Endocrine system is composed of various organs called what
glands
- chemical substances that are released into the blood in small amounts
- carried throughout the body by the circulatory system to distant target cells where they initiate physiological responses
hormones
- small, well-vascularized ductless glands composed of groups of cells arranged in cords or plates
- organ that produces hormones that are released into the bloodstream and travel to tissues and organs throughout the body
endocrine glands
have ducts for discharging their secretion onto a free surface
exocrine glands
ex. of exocrine glands
- sweat glands
- sebaceous glands
- salivary glands
Determines if the hormones cause widespread or extremely specialized reactions and at specified times
receptor molecules
Two kinds of receptors
- membrane-bound receptors
- nuclear receptors
- specialized protein molecules attached to or integrated into the cell membrane
- through interaction with specific ligands, they facilitate communication between the cell and the extracellular environment
Membrane receptors
What are the second-messenger systems known to participate in hormone actions
- cyclic AMP
- cyclic GMP
- calmodulin
- inositol trisphosphate
- diacylglycerol
family of ligand-regulated transcription factors that are activated by steroid hormones, and various other lipid-soluble signals
Nuclear receptors
- recognize short stretches of double-helical DNA of defined sequence
- determine which of the thousands of genes in a cell will be transcribed
Gene regulatory proteins
regulate color changes, growth, reproduction, and internal homeostatic mechanisms, such as metabolism, metabolic fuel levels, and osmoregulation
invertebrate hormones
Ex. of hormones in invertebrates
- peptides (often neuropeptides)
- steroids
- terpenoids (lipid-soluble organic molecules)
- principal source of hormones in many metazoan phyla
- resemble non-neural endocrine cells in their actions
- release hormones into the circulation and regulate a number of physiological responses
Neurosecretory cells
- products of neurosecretory cells and these are discharged directly into the circulation
- serve as a crucial link between the nervous and endocrine systems
Neurosecretory hormones
increases heart rate in Crustacea
Cardioactive peptide
hormones that regulate metabolism of carbohydrates, fats, and amino acids in Crustacea
Crustacean Hyperglycemic Hormone (CHH)
hormones that regulate metabolism of carbohydrates, fats, and amino acids in insects
Adipokinetic Hormone family
stimulate the secretion of fluid in insect Malpighian tubules
Diuretic hormones
- known to regulate muscular tissues of the body, and digestive and reproductive processes in many invertebrates, as well as osmoregulatory processes in nematodes, annelids, molluscs, and insects, and arterial hemolymph flow in crustaceans
- family of small neuropeptides
- appears to have evolved as early as bilateral symmetry
FMRFamide-related peptides (FaRPs)
These are primary controlled by the interaction of two hormones. One favoring growth and differentiation of adult structures and another favoring retention of juvenile structures
- molting
- metamorphosis
- steroid produced by the prothoracic gland
- controlled by prothoracicotropic hormone or PTTH
- polypeptide produced by neurosecretory cells of the brain, and transported by axons to the corpora cardiacum where it is stored.
- molting hormone or
- ecdysone
Molting hormone is also called as
ecdysone
Molting hormone or ecdysone is produced by what gland
prothoracic gland
Molting hormone is controlled by what
prothoracicotropic hormone (PTTH)
- terpenoid produced by the corpora allata
- appears to be important, at least in some insects, during diapause (or arrested development), which can occur at any stage of metamorphosis
juvenile hormones
Juvenile hormones are produced by what
corpora allata
usually occurs due to seasonal changes in environmental conditions, such as cold temperatures or changes in day length
Diapause
- small gland lying in a well-protected position between the roof of the mouth and floor of the brain
- two-part gland having a double embryological origin
Pituitary gland (hypophysis)
Pituitary gland is also called as
hypophysis
Two main sections of the pituitary gland
- Anterior pituitary (adenohypophysis)
- Posterior pituitary (neurohypophysis)
Anterior pituitary is also called as
adenohypophysis
Posterior pituitary is also called as
neurohypophysis
- front lobe of your pituitary gland
- produces and releases hormones
anterior pituitary
- does not produce hormones per se—this is done by nerve cells in the hypothalamus—but it does release them into the circulation
- store and release the hormones oxytocin and vasopressin (antidiuretic hormone)
posterior pituitary
contains groups of neurosecretory cells, which are specialized nerve cells that manufacture neurohormones called releasing hormones or release-inhibiting hormones (or “factors”)
hypothalamus
What are the neurohormones the hypothalamus manufacture
releasing hormones or release-inhibiting hormones
What does the hypothalamus manufacture
neurohormones
stop and start the production of other hormones throughout the body
releasing hormones or release-inhibiting hormones
Lobes of the anterior pituitary
- Anterior lobe (pars distalis)
- Intermediate lobe (pars intermedia)
How many hormones does the anterior pituitary produce
seven (7)
The seven (7) hormones produced by the anterior pituitary
- Thyroid-stimulating hormone (TSH) or thyrotropin
- Follicle-stimulating hormone (FSH)
- Luteinizing hormone (LH)
- Adrenocorticotropic hormone (ACTH)
- Prolactin
- Growth Hormone (somatotropin)
- Melanocyte-Stimulating Hormone (MSH)
Thyroid-stimulating hormone is also called as
thyrotropin
stimulates production of thyroid hormones by the thyroid gland
thyroid-stimulating hormone (TSH) or thyrotropin
Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are commonly known as what
gonadotropins
tropic hormones that act on
the gonads (ovaries of females, testes of males)
gonadotropins
group of hormones that stimulate other endocrine glands so as to produce their particular hormones
Tropic hormones
- promotes egg production
and secretion of estrogen (females) - supports sperm production (males)
Follicle-stimulating hormone (FSH)
- induces ovulation, corpus luteum production, and secretion of female sex steroids, progesterone and estrogen (female)
- promotes production of male sex steroids (primarily testosterone) (male)
Luteinizing hormone (LH)
Before it was discovered to be identical to LH in females, what was it once called in males?
Interstitial cell stimulating hormone (ICSH)
increases production and secretion of steroid hormones from the adrenal cortex
Adrenocorticotropic hormone (ACTH)
- essential for preparing mammary glands for lactation;
- after birth it is required for production of milk
- acts directly on its target tissues rather than through other hormones
Prolactin
formation of new blood vessels
angiogenesis
Growth hormone is also called as
somatotropin
- performs a vital role in governing body growth through its stimulatory effect on cellular mitosis, on synthesis of messenger RNA and protein, and on metabolism, especially in new tissue of young vertebrates
- acts directly on growth and metabolism, as well as indirectly through a polypeptide hormone produced by the liver
Growth hormone (somatotropin)
Insulin-like growth factor (IGF) is formerly called as
somatomedin
- formerly called somatomedin
- any of several peptide hormones that function primarily to stimulate growth but that also possess some ability to decrease blood glucose levels
Insulin-like growth factor (IGF)
- only anterior pituitary hormone produced by the intermediate lobe (except in birds and mammals)
- promotes dispersion of
the pigment melanin within melanocytes
Melanocyte-stimulating hormone (MSH)
source of two hormones of the posterior lobe of the pituitary
hypothalamus
Two hormones the posterior pituitary store and release
- Oxytocin
- Vasopressin
- two posterior-lobe hormones of mammals and are chemically very much alike
- Both are polypeptides consisting of eight amino acids (octapeptides)
- among the fastest-acting hormones, since they are capable of producing a response within seconds of their release from the posterior lobe
Oxytocin and Vasopressin
- stimulates contraction of uterine smooth muscles during parturition (birth of young)
- stimulates milk ejection by the mammary glands in response to suckling
Oxytocin
- acts on collecting ducts of the kidney to increase water reabsorption
- restrict urine flow
Vasopressin
Vasopressin is often called as
antidiuretic hormone (ADH)
increases blood pressure through its generalized constrictor effect on smooth muscles of arterioles
Vasopressin
increase thirst and drinking behavior
Vasopressin
- has the widest phylogenetic distribution
- considered the parent hormone from which other octapeptides evolved
Vasotocin
- occurs in all vertebrate except mammals
- water-balance hormone in amphibians
Vasotocin
Chemical nature of thyroid-stimulating hormone (TSH), follicle-stimulating hormone (FSH), luteinizing hormone (LH)
glycoprotein
Hypothalamic controls of thyroid-stimulating hormone (TSH)
TSH-releasing hormone (TRH)
Hypothalamic controls of follicle-stimulating hormone (FSH)
Gonadotropin-releasing hormone (GnRH)1
Hypothalamic controls of luteinizing hormone (LH)
- Gonadotropin-releasing hormone (GnRH)1
- Gonadotropin release-inhibiting hormone (GnIH)2
Chemical Nature of prolactin (PRL)
protein
Hypothalamic controls of prolactin (PRL)
- dopamine (prolactin release-inhibiting hormone or PIH)
- prolactin-releasing factor (PRF)?
Chemical Nature of growth hormone (GH) (somatotropin)
protein
Hypothalamic controls of growth hormone (GH) (somatotropin)
- growth hormone-releasing hormone (GHRH)
- growth hormone release-inhibiting hormone (GHIH) or somatostatin
Chemical nature of adrenocorticotropic hormone (ACTH)
polypeptide
Hypothalamic controls of adrenocorticotropic hormone (ACTH)
corticotropin-releasing hormone (CRH)
Chemical nature of melanocyte-stimulating hormone (MSH)
polypeptide
Hypothalamic controls of melanocyte-stimulating hormone (MSH)
melanocyte-stimulating hormone-inhibiting hormone (MSHIH)
Chemical nature of oxytocin, vasopressin, and vasotocin
octapeptide
- produces hormone melatonin
- in nonmammalian, is responsible for circadian rhythms
pineal gland
- strongly affected by exposure to light
- production is lowest during daylight and highest at night
Melatonin secretion
- self-generated (endogenous) rhythms that are about 24 hours in length
- serves as biological clock for many physiological processes that follow a regular pattern
circadian rhythms