chapter nine part two Flashcards
Krebs (citric acid) cycle
2C acetyl CoA + 4C oxaloacetate (oxaloacetic acid) –> 6C citric acid
how many Krebs cycles per glucose
2
vitamins needed for coenzyme NAD
niacin
vitamins needed for coenzyme FAD
riboflavin
vitamins needed for coenzyme CoA
pantothenic acid
products of pyruvate oxidation
2 acetyl CoA
2 CO2
2 NADH + H+
products of one acetyl CoA molecule per Krebs cycle
2 CO2
3 NADH
1 ATP (by SLP)
1 FADH2
products of one acetyl CoA per glucose
4 CO2
6 NADH
2 ATP
2 FADH2
how are NADH and FADH2 changed to ATP energy
electron transport chain - use high-energy electrons carried by NADH and FADH2
oxidative phosphorylation - ADP to ATP
how many ATP does oxidative phosphorylation produce?
30-32 ATP
what does oxidative phosphorylation involve?
free-energy change during electron transport
electron tranport chain
electrons move down chain of multi protein complexes, releasing free energy at every step
- includes cytochromes
- proteins and prosthetic groups
what is the final electron accepter?
oxygen - reacts w/ H+ to form water
where NADH enters the chain, how many ATP are made?
3 ATP per molecule
where FADH2 enters chain, how many ATP are made?
2
- comes later into chain and doesn’t build up as good as a gradient
ATP synthase
enzyme that makes ATP from ADP and P
- uses energy of existing ion gradient to power synthesis
- difference in concentration of H+ on either side of mitochondrial emmbrane
chemiosmosis
process in which energy stored in the form of H+ gradient across membrane is used to drive cellular work like synthesis of ATP
chemiosis in mitochondria
energy for gradient formation comes from exergonic redox reactions along ETC, ATP synthesis work is performed
- chemical energy converted to ATP energy
chemiosis in chloroplasts
ATP generated during photosynthesis
- light energy converted to ATP energy
chemiosis in bacteria and other prokaryotes
plasma membrane generates H+ gradient across PM
proton motive force and pump
force that promotes movement of protons across membrane down electrochemical potential
- force drives H+ back across membrane through H+ channels provided by ATP synthase
total ATP produced from glucose molecule in heart muscle, kidneys, and liver
38 - higher end
total ATP produced from glucose molecule elsewhere
36 - lower end
fermentation
harvesting chemical energy w/o O2 or ETC to produce ATP (less efficient)