Chapter 21 Part 2 Flashcards
Most basic immune response to get rid of pathogens during the first response
Innate immune response
A phagocyte is a cell that is able to surround and engulf a particle or cell
Phagocytosis
What are the characteristics of inflammation?
heat, redness, pain, and swelling (“loss of function” is sometimes mentioned as a fifth characteristic)
What happens during tissue injury?
released contents of injured cells stimulate the release of mast cell granules and their potent inflammatory mediators such as histamine, leukotrienes, and prostaglandins
increases the diameter of local blood vessels (vasodilation), causing an increase in blood flow; also increases the permeability of local capillaries
Histamine
causes increased blood flow and is responsible for the heat and redness of inflamed tissue. It allows greater access of the blood to the site of inflammation.
Vasodilation
causing leakage of fluid into the interstitial space, resulting in the swelling, or edema, associated with inflammation
Increased vascular permeability
failure of the immune system to protect the body adequately from infection, due to the absence or insufficiency of some component process or substance.
Immunodeficiency
not constitutively present in the body, but are made as they are needed early during the innate immune response; brings the phagocyte and bacterium into close proximity and enhances the phagocytosis of the bacterium
Early induced immune response
gene cluster whose proteins present antigens to T cells
Major histocompatibility complex