Ch 94: Antiviral Agents II: Drugs for HIV Infection and Related Opportunistic Infections Flashcards by Dana Ellis | Brainscape

Q

HIV is a retrovirus. Like all other viruses, retroviruses lack the machinery needed for ___-___________, and thus are…

A

self-replication;
obligate intracellular parasites

(p. 1125)

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Q

Nucleoside/nucleotide reverse transcriptase inhibitors (NTRIs) work by…

A

…suppressing synthesis of viral DNA by reverse transcriptase.

(p. 1128)

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Q

What are the principal toxic effects of NRTIs?

A

Severe anemia and neutropenia secondary to bone marrow suppression.

(p. 1128)

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