Ch 94: Antiviral Agents II: Drugs for HIV Infection and Related Opportunistic Infections Flashcards
1
Q
HIV is a retrovirus. Like all other viruses, retroviruses lack the machinery needed for ___-___________, and thus are…
A
self-replication;
obligate intracellular parasites
(p. 1125)
2
Q
Nucleoside/nucleotide reverse transcriptase inhibitors (NTRIs) work by…
A
…suppressing synthesis of viral DNA by reverse transcriptase.
(p. 1128)
3
Q
What are the principal toxic effects of NRTIs?
A
Severe anemia and neutropenia secondary to bone marrow suppression.
(p. 1128)
