Ch 36: Central Nervous System Stimulants and Attention-Deficit/Hyperactivity Disorder

Question 1

What are the 2 principal indications for CNS stimulants?

Answer 1

ADHD and narcolepsy

p. 395

Question 2

How do antidepressants and CNS stimulants vary?

Answer 2

Antidepressants act selectively to elevate mood. CNS stimulants cannot elevate mood w/o producing generalized excitation.

(p. 395)

Question 3

What does the term amphetamine refer to?

Answer 3

A 50:50 mixture of dextroamphetamine and levamphetamine.

p. 396

Question 4

What does the term racemic mean?

Answer 4

an equimolar mixtures of enantiomers

p. 396

Question 5

What is the MOA of amphetamines?

Answer 5

The act by causing release of NE and DA, and partly by inhibiting their reuptake.

(p. 396)

Question 6

With regular amphetamine use, tolerance develops to…

Answer 6

…elevation of mood, suppression of appetite, and stimulation of the heart and blood vessels.

(p. 396)

Question 7

In the periphery, caffeine promotes ____________, whereas in the CNS, caffeine promotes ____________.

Answer 7

vasodilation
vasoconstriction

(p. 399)

Question 8

Stimulants do not create positive behavior, they only…

Answer 8

…reduce negative behavior.

p. 401