Ch 104: Drugs for the Eye

Question 1

Glaucoma refers to a group of diseases characterized by…

Answer 1

…visual field loss secondary to optic nerve damage.

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Question 2

What are the most common forms of glaucoma?

Answer 2

primary open-angle glaucoma (90% of people with glaucoma have this type)

acute angle-closure glaucoma

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Question 3

In the eye, aqueous humor is produced by the _______ ____ and secreted into the _________ _______ of the eye.

Answer 3

ciliary body; posterior chamber

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Question 4

The principal method for reducing IOP is…

Answer 4

…chronic therapy with drugs.

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Question 5

Drugs lower IOP by either (1) or (2).

Answer 5

(1) facilitating aqueous humor outflow
(2) reducing aqueous humor production

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Question 6

What 3 classes of drugs are first-line agents for glaucoma?

What 2 classes are second-line agents?

Answer 6

1) beta-adrenergic blocking agents
2) alpha2-adrenergic agonists
3) prostaglandin analogs

1) cholinergic drugs
2) carbonic anhydrase inhibitors