Ch 58: Drugs for Thyroid Disorders

Question 1

Thyroid hormones stimulate the _________ ____ of most cells, and increase the force and rate of _______ ___________.

Answer 1

metabolic rate; cardiac contraction

p. 703

Question 2

The biologic effects of T3 and T4 are qualitatively similar, however, on a molar basis, which is more potent?

Answer 2

T3

p. 703

Question 3

What are the 3 principal actions of thyroid hormones?

Answer 3

1) stimulation of energy use
2) stimulation of the heart
3) promotion of growth and development

(p. 703)

Question 4

In primary hypothyroidism, TSH levels are…

Answer 4

…high.

p. 705

Question 5

In secondary hypothyroidism, resulting from anterior pituitary dysfunction, TSH levels are…

Answer 5

…low, normal, or even slightly elevated, despite the presence of low levels of T3 and T4.
(p. 705)