Ch 7 - Action Potential Flashcards

0
Q

ap is propagated with the same blank and blank along the whole length of the nerve or muscle cell

A

size, shape

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1
Q

action potential is a rapid and momentary change in blank of a nerve or muscle cell when excited resulting the transmission of a blank signal

A

membrane potential, electric

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2
Q

property of ap that limits the frequency of them

A

refractory period

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3
Q

the ap is blank so it does not lose strength of signal

A

self regenerative

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4
Q

ap results from increase in ionic blank

A

ionic conductance

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5
Q

a voltage clamp blank the voltage by not allowing the blank to change

A

fixes, membrane potential

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6
Q

the blank maintains the command voltage by sending current out if there is current coming in and vice versa

A

feedback amplifier

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7
Q

a sudden hyperpolarization results in a transient blank current but not blank currents

A

capacitative, ionic

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8
Q

the blank current is very short lived

A

capacitative

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9
Q

resting ion channels are aka blank channels

A

leakage

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10
Q

no blank channels have net current during hyperpolarization, but they have a net current during blank

A

leakage, depolarization

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11
Q

current above 0 is blank

A

outward

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12
Q

voltage gated sodium and potassium channels open when blank depolarization signal is given to the cell

A

large

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13
Q

to study the current of only K+ ions, sodium ions were replaced with a blank so only the potassium flowed

A

impermeable choline ion

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14
Q

ttx is

A

tetradotoxin

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15
Q

ttx blocks blank ion channels

A

sodium voltage gated

16
Q

ttx is produced by blank

A

puffer fish

17
Q

these two block sodium channels

A

ttx, saxitoxin

18
Q

these two block potassium channels

A

aminopyridine, TEA

19
Q

TEA has a blank affinity so it takes blank of the drug to have an effect

A

low, a lot

20
Q

dominant ion on inside of cell

A

potassium

21
Q

with a prolonged depolarization signal, blank channels NEVER close but blank do

A

potassium, sodium

22
Q

measurements of gna and gk at various levels of membrane potentials reveal two functional similarities and two differences

A

2 similarities

  1. both open in response to depolarization
  2. as size of depolarization increases probability R rate of opening of Na and K channels increase

2 differences

  1. (rate of opening) sodium channels open more rapidly at depolarizing potentials than potassium channels
  2. (response to prolonged depolarzation) when depolarization is maintained for a long period of time, sodium channels begin to close which causes a decreased inward current…. potassium channels remain open
23
Q

process by which sodium channels close during a prolonged depolarization is termed blank

A

inactivation

24
Q

channel is only open during the brief period of time when blank gates are open

A

activation/inactivation

25
Q

activation gate is closed at blank

A

resting membrane potential

26
Q

activation gate opens by blank signal

A

depolarization

27
Q

inactivation gate is open at blank

A

resting membrane potential

28
Q

inactivation gate closes during

A

prolonged depolarization