Ch 7 - Action Potential Flashcards

0
Q

ap is propagated with the same blank and blank along the whole length of the nerve or muscle cell

A

size, shape

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1
Q

action potential is a rapid and momentary change in blank of a nerve or muscle cell when excited resulting the transmission of a blank signal

A

membrane potential, electric

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2
Q

property of ap that limits the frequency of them

A

refractory period

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3
Q

the ap is blank so it does not lose strength of signal

A

self regenerative

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4
Q

ap results from increase in ionic blank

A

ionic conductance

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5
Q

a voltage clamp blank the voltage by not allowing the blank to change

A

fixes, membrane potential

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6
Q

the blank maintains the command voltage by sending current out if there is current coming in and vice versa

A

feedback amplifier

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7
Q

a sudden hyperpolarization results in a transient blank current but not blank currents

A

capacitative, ionic

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8
Q

the blank current is very short lived

A

capacitative

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9
Q

resting ion channels are aka blank channels

A

leakage

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10
Q

no blank channels have net current during hyperpolarization, but they have a net current during blank

A

leakage, depolarization

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11
Q

current above 0 is blank

A

outward

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12
Q

voltage gated sodium and potassium channels open when blank depolarization signal is given to the cell

A

large

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13
Q

to study the current of only K+ ions, sodium ions were replaced with a blank so only the potassium flowed

A

impermeable choline ion

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14
Q

ttx is

A

tetradotoxin

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15
Q

ttx blocks blank ion channels

A

sodium voltage gated

16
Q

ttx is produced by blank

A

puffer fish

17
Q

these two block sodium channels

A

ttx, saxitoxin

18
Q

these two block potassium channels

A

aminopyridine, TEA

19
Q

TEA has a blank affinity so it takes blank of the drug to have an effect

A

low, a lot

20
Q

dominant ion on inside of cell

21
Q

with a prolonged depolarization signal, blank channels NEVER close but blank do

A

potassium, sodium

22
Q

measurements of gna and gk at various levels of membrane potentials reveal two functional similarities and two differences

A

2 similarities

  1. both open in response to depolarization
  2. as size of depolarization increases probability R rate of opening of Na and K channels increase

2 differences

  1. (rate of opening) sodium channels open more rapidly at depolarizing potentials than potassium channels
  2. (response to prolonged depolarzation) when depolarization is maintained for a long period of time, sodium channels begin to close which causes a decreased inward current…. potassium channels remain open
23
Q

process by which sodium channels close during a prolonged depolarization is termed blank

A

inactivation

24
channel is only open during the brief period of time when blank gates are open
activation/inactivation
25
activation gate is closed at blank
resting membrane potential
26
activation gate opens by blank signal
depolarization
27
inactivation gate is open at blank
resting membrane potential
28
inactivation gate closes during
prolonged depolarization