Ch 10 - Synaptic Integration in CNS Flashcards
a central neuron can receive blank or blank input
excitatory, inhibitory
a central nerve cell receives connections from blank neurons
100s-1000s
a single central neuron responds to different inputs, each mediated by a distinct transmitter called a blank
neurotransmitter
binding of neurotransmitter directly opens ion channel in this receptor
ionotropic
binding of transmitter indirectly regulates a channel by second messengers in this receptor
metabotropic
glutamate causes blank in the brain
excitation
gaba and glycine cause blank in the cns
inhibitory
when ipsp’s shape the pattern of firing
sculpting
type 1 synaptic terminals
glutamatergic
type 2 synaptic terminals
gabaergic
there is a blank density of receptors in type 1 but not in type 2
high
type 1 synaptic terminal is more dendritic and synapses at blank of the neuron
spine
glutamate excitatory post synaptic current
central synapse
2 epsc
nmda, ampa
at resting membrane potential, blank block the pore of blank channels
magnesium, nmda
drug that blocks nmda receptors
apv
the currents seen with apv will be only blank because blank are blocked
ampa, nmda
current decay without nmda is much blank
slower
reversal potential is when the current is blank
0
when the trigger zone has a high density of blank channels, the threshold is blank
sodium, low
a dendrite has a blank action potential
back propagating
an axon has a blank action potential
forward propagating
strong depolarizing blank generates ap
epsp