ch 5- cell division Flashcards
homologous chromosome pairs
two diff versions of the same chromsome number
one from mom and one from dad
dyad
replicated chromosomes containing two sister chromatids that look like an X
connected by centromeres
what connects sister chromatids
centromeres
kinetochores
proteins on the side of centromeres that help microtubules pull sister chromatids apart during cell idvision
karyokinesis
division of the nucleus
how many autosomes do we have (chromosomes)
22 pairs
gametes
haploid cells (sperm and eggs)
germ cells
diploid cells that divide by meiosis to produce gametes
gametocyte
euk germ cell
can either divide to make more gametocyte or produce gametes
what are somatic cells
ALL BODY CELLS EXCEPT GAMETES (haploid)
what are the parts of interphase
G1
G0
S
G2
90% of the cell cycle happens during what
interphase
what happens during G1
cell grows
checks for favourable conditions
if unfavourable it will enter G0
what is G0
cells still carry functions but stop cell cycle and do not divide
what happens during S phase
cell replicates its genome
centrosome replicates
what happens during G2
continues to grow
check DNA for errors
checks for MPF- mitosis promoting factor (maturation promoting factor)
organelles replicated
what are the fucntional limitations that lead to cell division
when surface area: volume ratio is too low and when the genome to volume ratio is too low
what are the cell specific checkpoints
G1- check for facourable conditions
end of G2- check for errors in DNA and MPF levels
M- check for chromosomal attachment to spindle fibres
CDKs
phosphorylate certain substrates to signal cell cycle progression
they depend on cyclin which cycles through stages of synth and degradation
growth factors
bind to receptors in th eplasma membrane to signal for cell division
density dependent inhibition
halting cell division when density of cells is high
anchorage dependence
cells divide only when attached to an external surface
what forms the spindle apparatus
the MTOCs
MTOCs
organize spindle appartus
ONLY IN EUK-
made up of centrosomes- pair of centromeres- ORGANELLES