ch 5- cell division Flashcards

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1
Q

homologous chromosome pairs

A

two diff versions of the same chromsome number

one from mom and one from dad

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2
Q

dyad

A

replicated chromosomes containing two sister chromatids that look like an X

connected by centromeres

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3
Q

what connects sister chromatids

A

centromeres

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4
Q

kinetochores

A

proteins on the side of centromeres that help microtubules pull sister chromatids apart during cell idvision

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5
Q

karyokinesis

A

division of the nucleus

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6
Q

how many autosomes do we have (chromosomes)

A

22 pairs

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7
Q

gametes

A

haploid cells (sperm and eggs)

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8
Q

germ cells

A

diploid cells that divide by meiosis to produce gametes

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9
Q

gametocyte

A

euk germ cell

can either divide to make more gametocyte or produce gametes

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10
Q

what are somatic cells

A

ALL BODY CELLS EXCEPT GAMETES (haploid)

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11
Q

what are the parts of interphase

A

G1
G0
S
G2

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12
Q

90% of the cell cycle happens during what

A

interphase

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13
Q

what happens during G1

A

cell grows

checks for favourable conditions

if unfavourable it will enter G0

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14
Q

what is G0

A

cells still carry functions but stop cell cycle and do not divide

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15
Q

what happens during S phase

A

cell replicates its genome

centrosome replicates

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16
Q

what happens during G2

A

continues to grow

check DNA for errors

checks for MPF- mitosis promoting factor (maturation promoting factor)

organelles replicated

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17
Q

what are the fucntional limitations that lead to cell division

A

when surface area: volume ratio is too low and when the genome to volume ratio is too low

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18
Q

what are the cell specific checkpoints

A

G1- check for facourable conditions

end of G2- check for errors in DNA and MPF levels

M- check for chromosomal attachment to spindle fibres

19
Q

CDKs

A

phosphorylate certain substrates to signal cell cycle progression

they depend on cyclin which cycles through stages of synth and degradation

20
Q

growth factors

A

bind to receptors in th eplasma membrane to signal for cell division

21
Q

density dependent inhibition

A

halting cell division when density of cells is high

22
Q

anchorage dependence

A

cells divide only when attached to an external surface

23
Q

what forms the spindle apparatus

A

the MTOCs

24
Q

MTOCs

A

organize spindle appartus

ONLY IN EUK-

made up of centrosomes- pair of centromeres- ORGANELLES

25
Q

What are the types of microtubules in the spindle appartus

A

kinetochore microtubules

astral microtubules

polar microtubules

26
Q

kinetochore microtubules

A

extend from centrosomes and attach to kinetochores on chromosomes

27
Q

astral microtubules

A

extend from centrosomes to the cell membrane to orient the spindle apparatus

28
Q

polar microtubules

A

extend from the two centrosomes and connect with each other - push centrosomes to opposite ends of the cell

29
Q

pericentriolar material

A

surrounds centrioles and is responsible for microtubule nucleation (anchoring tubulin to start microtubule extension)

30
Q

prophase

A

chromatin condenses

nucleolus and nuclear envelope dissapear

spindle apparatus forms

31
Q

prometaphase

A

nuclear envelope fragments

spindle apparatus microtubules attach to kinetochore of chromosomes

32
Q

when does chromosomes number double

A

during anaphase

33
Q

cleavage furrow

A

forms in late anaphase in animal cells

contractile ring of ACTIN microfillaments and myosin motors that pinches the cell into two

34
Q

cell plate

A

in telophase in plant cells

created by vesicles form the golgi apparatus and forms middle lamella (cements plant cells together)

35
Q

binary fission

A

no s phase

cells replicate genome DURING cell division

NO SPINDLE APPARATUS

36
Q

Meiois I vs II

A

I- homologous chromosomes separate

II- sister chromosomes separate - reductional division

37
Q

when does crossing over occur

A

prophase I

38
Q

bivalent

A

tetrads - homologous chromosomes paired up - happens during synapsis

between these homologous chromosomes, there is a synaptonemal complex

39
Q

chiasmata

A

when two chromosomes of a homologous pair cross over during synapsis

40
Q

s phase chromosome numbers

A

there are 46 chromosomes- after duplication- there are still 46 chromosomes but 92 chromatids

during anaphase- we have 92 chromosomes and 92 chromatids and results in 46 chromosomes and 46 chromatids after separation (diploid)

41
Q

number of chromosomes and chromatids in mitosis

A

prophase - 46. 92
metaphse- 46. 92
anaphase- 92. 92
telophase- 92. 92

separated cells have 46 chromosomes and chromatids

42
Q

number of chromosomes and chromatids in meiosis I

A

prophase - 46. 92
metaphse- 46. 92
anaphase- 46. 92
telophase- 46. 92

separated cells have 23 chromosomes and 46 chromatids

43
Q

number of chromosomes and chromatids in meiosis II

A

prophase - 23. 46
metaphse- 23. 46
anaphase- 46. 46
telophase- 46. 46

separated cells have 23 chromosomes and 23 chromatids