Ch. 16 Vocab Flashcards
a virus that infects bacteria; aka a phage
bacteriophages
the form of native DNA, referring to its two adjacent antiparallel polynucleotide strands wound around an imaginary axis into a spiral shape
double helix
type of DNA replication in which the replicated double helix consists of one old strand, derived from the old molecule, and one newly made strand
semiconservative model
site where the replication of a DNA molecule begins, consisting of a specific sequence of nucleotides
origins of replication
a Y-shaped region on a replicating DNA molecule where the parental strands are being unwound and new strands are growing
replication fork
an enzyme that untwists the double helix of DNA at the replication forks, separating the two strands and making them available as template strands
helicases
a protein that breaks, swivels, and rejoins DNA strands; helps relieve strain in the double helix ahead of the replication fork during DNA replication
topoisomerase
a short stretch of RNA with a free 3’ end, bound by complementary base pairing to the template strand, that is elongated with DNA nucleotides during DNA replication
primer
an enzyme that catalyzes the elongation of new DNA by the addition of nucleotides to the 3’ end of an existing chain
DNA polymerases
the new complementary strand synthesized continuously along the template strand toward the replication fork in the mandatory 5’–>3’ direction
leading strand
a discontinuously synthesized DNA strand that elongates by means of Okazaki fragments, each synthesized in a 5’–>3’ direction away from the replication fork
lagging strand
a short segment of DNA synthesized away from the replication fork on a template strand during DNA replication, many of which are joined together to make up the lagging strand of newly synthesized DNA
Okazaki fragments
a linking enzyme essential for DNA replication; catalyzes the covalent bonding of the 3’ end of one DNA fragment to the 5’ end of another DNA fragment
DNA ligase
an enzyme that cuts DNA or RNA, either removing one or a few bases or hydrolyzing the DNA or RNA completely into its component nucleotides
nuclease
the tandemly repetitive DNA at the end of a eukaryotic chromosome’s DNA molecule that protects the organism’s genes from being eroded during successive rounds of replication
telomeres