Cerebellum Flashcards
exam 1
cerebellum are connected by
cerebellar peducles
inferior cerebellum is found in the ______ and mostly contains ____ to cerebellum
found in the medulla and mostly contains inputs to cerebellum
Middle cerebellum found in ______
`and contains only ____ to cerebellum
found in pons and only input to cerebellum
superior cerebellum found in ______ and contains mostly _____ from cerebellum
found in midbrain and mostly contain output from cerebellum
lesions in cerebellar leads to
ipsilateral deficits
does the cerebellum contain more neurons than the cerebral cortex?
heck yea
what is vulnerable for occlusion?
4th ventricle
Mollaret’s triangle
is a sel-contained circuit involving the inferior olive, dentate and red nucleus
climbing fibers from the inferior olive go where?
direct to the purkinje fibers
what is the order in which cells receives the input in the cerebellum?
internal granular (packed with cells) —> Molecular —>Purkinje
most incoming fibers synapse on
granular cell dendrites
what are the deep cerebellar nuclei?
output nuclei
vermis involved with
trunkal control
flocculondular lobe?
vestibulocerebellum
vestibulocerebellum receives input t (and its output is to) ________ and when lesioned it affects
input from vestibular nuclei and when lesioned it affects balance and gait ataxia
spinocerebellum receives input (and its output is to) _______from and when lesioned it affects
receives input from spinocerebellar tract and olives and when lesioned it affects trunkal coordination
Neocerebellum input is from _______ and output is ________
input: cortex via pontine nuclei
output: back to cortex via VL of thalamus
neocerebellum lesioned affect
upper extremities dyscoordination
vascular syndrome of the cerebellum that are caused by" - hemorrhage/infarct -toxic exposure - heat stroke anoxia
acute cerebellar disease
Subacute cerebellar disease:
- alcoholic–>
- Praneoplastic –>
- Cerebellar tumors –>
- MS –>
- alcoholic–> vermis
- Praneoplastic –> antibodies vs. purkinje cells leading to cerebellar ataxia
- Cerebellar tumors –> occlusion of the 4th ventricle
- MS –> cerebellum white fibers
inherent disease of the cerebellum that can be caused by:
- congenital cerebellar hypoplasia
- genetic disorders like spinocerebellar ataxia
- neurodegenerative like olivopontocerebellar degeneration that has parkisonian like features
- metabolic diseases
chronic cerebellar disease
How does the cerebellum differ in its representation of the body?
ipsilateral strcuture
what does this mean for input and output?
remains ipsilateral or crosses twice
what is carried in each peduncle?
superior:
middle:
inferior:
superior: output
middle: cortico-ponto-cerebellar fibers
inferior: spinocerebellar, vestibulocerebellar
How is the cerebellar cortex organized?
input to granular, synapse on purkinje cell in molecular
Purkinje cell to deep nuclei
what are the functional divisions?
lateral, vermis and paravermis, flocculonodular
Clinical symptoms of cerebellum issues
- nystagmus
- incoordination, intention tremor
- dysdiadochokinesis
- hypotonia- flaccid tone
dysdiadochokinesis
rapid, altering movements
lesion within the mollaret’s triangle
palatal myoclonus