neurocytology Flashcards

exam 1

1
Q

myelin-axons are found at

A

white matter

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2
Q

staining of the nucleus and cytoplasm

A

H&E

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3
Q

staining of nucleus, rough endoplasmic reticulum

A

Nissl

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4
Q

signal transmission is

A

directional

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5
Q

astroglia are especially important due to their role in

A

uptake of glutamate through excitatory a.a. transporters (EAATs)

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6
Q

astroglia are ______ excitable and very _____ resistance

A

astroglia are non-electrically excitable, and very low input-resistance

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7
Q

Tripartite synapse

A

the relationship between the presynaptic and postsynaptic cells and how astrocytes are close to them.

they are the ones that play a role with taking up glutamate

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8
Q

how do astrocytes respond to synaptic signals

A

Calcium excitability

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9
Q

Glutamate-Glutamine cycle

A

this cycle explains how glutamate is taken up by the astrocytes and then converted to Glutamine which then can be recycled into Glutamate again in the presu=ynaptic cells

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10
Q

Astrocytes become _______ to form Glial scars in injury

A

astrocytes become GFAP+ to form Glial scars

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11
Q

true or false:

certain reactive astroglia are toxic and are able to induce cell death by secreting toxic factors

A

true

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12
Q

major source of brain glioma

A

astrocytoma

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13
Q

microglia functions

A
surveillance
release of cytokines  following activation
cluster around amyloid plaques
phagocytosis
high motility
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14
Q

APOE4

A

most common glia gene for alzheimer;s and it has a medium risk

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15
Q

PSEN and APP

A

are rare glia genes connected to alzheimers and it carries a high risk

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16
Q

oligodendrocytes are involved with myelin formation in the

A

CNS

17
Q

schwann cells are invovled in Myelin formation in the

A

PNS