neurocytology Flashcards
exam 1
myelin-axons are found at
white matter
staining of the nucleus and cytoplasm
H&E
staining of nucleus, rough endoplasmic reticulum
Nissl
signal transmission is
directional
astroglia are especially important due to their role in
uptake of glutamate through excitatory a.a. transporters (EAATs)
astroglia are ______ excitable and very _____ resistance
astroglia are non-electrically excitable, and very low input-resistance
Tripartite synapse
the relationship between the presynaptic and postsynaptic cells and how astrocytes are close to them.
they are the ones that play a role with taking up glutamate
how do astrocytes respond to synaptic signals
Calcium excitability
Glutamate-Glutamine cycle
this cycle explains how glutamate is taken up by the astrocytes and then converted to Glutamine which then can be recycled into Glutamate again in the presu=ynaptic cells
Astrocytes become _______ to form Glial scars in injury
astrocytes become GFAP+ to form Glial scars
true or false:
certain reactive astroglia are toxic and are able to induce cell death by secreting toxic factors
true
major source of brain glioma
astrocytoma
microglia functions
surveillance release of cytokines following activation cluster around amyloid plaques phagocytosis high motility
APOE4
most common glia gene for alzheimer;s and it has a medium risk
PSEN and APP
are rare glia genes connected to alzheimers and it carries a high risk