CCC 5 Flashcards

1
Q

what are the causes of bloody diarrhoea?

A

infection- infectious colitis
inflammation- ulcerative colitis
ischaemic colitis

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2
Q

how does portal hypertension present?

A

ascites
SBP
hepatic encephalopathy
variceal bleed

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3
Q

what will be findings and symptoms in someone with HUS?

A

haemolysis= shistocytes on blood film
uraemia= high creatinine
recent diarrhoea and malaise

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4
Q

whats the triad for HUS?

A

haemolytic anaemia
uraemia
thrombocytopenia

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5
Q

what are the 3 hereditary haemolytic anaemias and what defects do they have?

A

G6PD deficiency- deficiency in the enzyme causes breakdown of RBCs
hereditary spherocytosis- defect in the cell membrane causes breakdown of RBCs
sickle cell/thalassaemia- haemoglobinopathy

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6
Q

what are the acquired causes of haemolytic anaemia?

A

autoimmune
MAHA
drugs
infection

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7
Q

what is the difference between small and large bowel obstruction on x ray?

A

small bowel= valvulae conniventes

large bowel= haustra

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8
Q

what are the cuases of hypovolemic hyponatraemia?

A

vomitting
diarrhoea
diuresis

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9
Q

how do you identify hypovolemic hyponatraemia?

A

you have to do a urine sodium not serum

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10
Q

what are the causes of euvolemic hyponatraemia?

A

SIADH

hypothyrodisim

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11
Q

why does hypothyroidism cause euvolemic hyponatraemia?

A

hypothyroidism causes reduced cardiac output
this causes increased release of ADH
higher levels of ADH will cause more sodium excretion

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12
Q

what are the causes of hypervolemic hypontraemia?

A

liver, heart and kidney failure

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13
Q

how do you differentiate hypovolemic and hypervolemic hyponatraemia using ix?

A
hypovolemic= high urine sodium
hypervolemic= low urine sodium
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14
Q

what are the micro, macro and metolbic complications of diabetes?

A
micro= retinopathy, nephropathy, neuropathy
macro= stroke, MI, PVD
metab= DKA, HHS, hypoglycaemia
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15
Q

what are the 2 sources of ALP?

A

lung and bone

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16
Q

what will ALP level be in myeloma?

A

normal

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17
Q

what are the causes of cavitating lung lesions?

A

infection= klebsiella, staph aureus, TB
inflammation= rheumatoid arthritis
malignancy
ischaemia= PE

18
Q

what should you think if someone has recurrent GI and nosebleeds?

A

hereditary telangiectasia

19
Q

what are the 3 components of FBC?

A

Hb
WCC
platelets

20
Q

what acronym is used to remember the causes of macrocytic anaemia?

A
alcoholics may have liver failure: 
alcohol
myelodysplasia
hypothyroidism
liver failure 
folate/b12 deficiency
21
Q

what are symptoms of polycythaemia vera?

A
headache 
tinnitus 
pruritus after a hot bath
thrombosis 
DVT
blurred vision
22
Q

what are the 4 main presentations of sickle cell (acutely) and how are they managed?

A
acute painful crisis= o2, analgesia, abx, IV fluids 
sequestration crisis (bone pain)= if repeated do splenectomy 
cholecystitis= do a cholecystectomy 
stroke= exchange blood transfusion
23
Q

what are the 4 presentations of sickle cell?

A

acute painful crisis
cholecystitis
sequestration crisis
stroke

24
Q

how do you manage a stroke due to sickle cell?

A

exchange blood transfusion

25
Q

what are the crab features of multiple myeloma and how do they present?

A

c- hypercalcaemia= polyuria, polydipsia and constipation
r-renal failure= high urea and creatinine
a- anaemia=SOB, pallor
b- bone pain

26
Q

if there is anaemia with low reticulocytes, what might be the cause?

A

parvovirus B
aplastic crisis with sickle cell
blood tranfusion

27
Q

what will you see on an uptake scan in thyroid cancer?

A

cold nodules

28
Q

what are rf for thyroid cancer?

A

irradiation
fhx
lymphadenopathy

29
Q

how do you treat a bitemporal hemianopia first line?

A

cabergoline not surgery

30
Q

how is prolactinoma managed first line and why?

A

cabergoline not surgery

surgery is very risky

31
Q

when diagnosing cushings what should you look for and what can help you differentiate it?

A

if they are just depressed and have gained weight this is not cushings
look for purple striae, bruising, thin skin, young onset diabetes/hypertension/ osteoporosis

32
Q

what is the relationship between potassium and glucose?

A

potassium drives glucose into cells therefore hypokalemia causes diabetes

33
Q

what are the causes of oligo/amenorrhea and how do you remember?

A

go from head to toe:
hypothalamus (excess exercise or low BMI)
pituitary (excess prolactin/lack of FSH or LH)
thyroid (do TFTs)
PCOS (hyperandrgenism causes lack of negative feedback)

34
Q

what 3 blood tests should you do for polyuria and polydipsia and why?

A

blood glucose, potassium and calcium

low potassium and calcium cause diabetes

35
Q

what causes hypernatraemia if there is high urine osmolality?

A

dehydration, HHS or T2DM

36
Q

what causes hypernatraemia if there is low urine osmolality?

A

diabetes insipidus

37
Q

what should you think when you see high calcium with low PTH?

A

malignancy or myeloma

38
Q

what is active urine sediment?

A

blood and protein in urine

39
Q

how does renal artery stenosis present?

A

asymmetrical kidneys

40
Q

what ix is done for renal artery stenosis?

A

magnetic resonance angiography

41
Q

what are features of BCC?

A

pearly
rolled edges
surface telangiectasia
rolled edges