CCC 5 Flashcards
what are the causes of bloody diarrhoea?
infection- infectious colitis
inflammation- ulcerative colitis
ischaemic colitis
how does portal hypertension present?
ascites
SBP
hepatic encephalopathy
variceal bleed
what will be findings and symptoms in someone with HUS?
haemolysis= shistocytes on blood film
uraemia= high creatinine
recent diarrhoea and malaise
whats the triad for HUS?
haemolytic anaemia
uraemia
thrombocytopenia
what are the 3 hereditary haemolytic anaemias and what defects do they have?
G6PD deficiency- deficiency in the enzyme causes breakdown of RBCs
hereditary spherocytosis- defect in the cell membrane causes breakdown of RBCs
sickle cell/thalassaemia- haemoglobinopathy
what are the acquired causes of haemolytic anaemia?
autoimmune
MAHA
drugs
infection
what is the difference between small and large bowel obstruction on x ray?
small bowel= valvulae conniventes
large bowel= haustra
what are the cuases of hypovolemic hyponatraemia?
vomitting
diarrhoea
diuresis
how do you identify hypovolemic hyponatraemia?
you have to do a urine sodium not serum
what are the causes of euvolemic hyponatraemia?
SIADH
hypothyrodisim
why does hypothyroidism cause euvolemic hyponatraemia?
hypothyroidism causes reduced cardiac output
this causes increased release of ADH
higher levels of ADH will cause more sodium excretion
what are the causes of hypervolemic hypontraemia?
liver, heart and kidney failure
how do you differentiate hypovolemic and hypervolemic hyponatraemia using ix?
hypovolemic= high urine sodium hypervolemic= low urine sodium
what are the micro, macro and metolbic complications of diabetes?
micro= retinopathy, nephropathy, neuropathy macro= stroke, MI, PVD metab= DKA, HHS, hypoglycaemia
what are the 2 sources of ALP?
lung and bone
what will ALP level be in myeloma?
normal