Cardio - Systemic Hypertension Flashcards
How is BP measured?
Directly (intra-arterial) or indirectly (doppler/oscillometric)
What BP measurement is more accurate for smaller patients?
Doppler
Where should BP be measured in cats?
tail base
Where should BP be measured in dogs?
non-dependent limbs
How big should the BP cuff be in dogs vs. cats?
Dogs = 40% of circumference
Cats = 30-40% of circumference
What causes SHT in humans?
95% primary
What type of SHT do dogs and cats have?
secondary (esp. animals > 10 yo)
What diseases cmmonly have secondary SHT in dogs?
Hyperadrenocorticism, CKD
What diseases commonly have secondary SHT in cats?
hyperthyroidism, CKD
Heart disease _____ cause SHT, but SHT can _____ or _____ heart disease.
does not, cause, worsen
What organs are more prone to SHT?
Kidney, eye, brain, heart, blood vessels
What damage does SHT have on the kidneys?
Progression of CKD, proteinuria
What damage does SHT have on the eye?
Retinal hemorrhage and detachment
What damage does SHT have on the brain?
Hemorrhagic stroke
What damage does SHT have on the heart?
LV hypertrophy
What damage does SHT have on blood vessels?
hemorrhage
What clinical signs are associated with SHT and the kidney?
PU/PD
What clinical signs are associated with SHT and the eye?
acute blindness
What clinical signs are associated with SHT and the brain?
Forebrain signs, seizures
What clinical signs are associated with SHT and the heart?
heart murmur, S4 gallop, CHF
What clinical signs are associated with SHT and blood vessels?
Epistaxis
What diagnostic tests can be run when SHT is suspected to involve the kidney?
BUN/crea, U/A, UP:C
What diagnostic tests can be run when SHT is suspected to involve the eye?
fundic exam
What diagnostic tests can be run when SHT is suspected to involve the brain?
neuro exam, MRI
What diagnostic tests can be run when SHT is suspected to involve the heart?
Echo
What diagnostic tests can be run when SHT is suspected to involve the blood vessels?
PE
What is normal BP (systolic)?
120-130 mmHg
What happens in “white coat” effect?
Situational hypertension, no official cutoff for high BP in a very stressed patient
What is abnormal BP (systolic) AKA SHT?
>140 mmHg
What BP range is considered pre-hypertensive?
What is the risk of future target organ damage?
140-159; mild
What BP range is considered truly hypertensive?
What is the risk of future target organ damage?
160-179; moderate
What BP range is considered severely hypertensive?
What is the risk of future target organ damage?
>180; severe
What 4 types of patients should be screened for SHT?
- Those with evidence of target organ damage
- Those with diseases that cause secondary SHT
- Those receiving vasodilator therapy
- Those with diseases that are worsened by SHT (DMVD)
When is routine BP screening recommended?
Dogs and cats >9 years
A

Systolic BP >160 mmHg
B

Evidence of TOD
C

TREAT!
D

No evidence of TOD
E

BP 160-179 mmHg: repeat BP twice within 8 weeks
F

<160 mmHg: recheck in 3-6 months
G

>160 mmHg: TREAT
H

BP > 180 mmHg: repeat BP twice within 2 weeks
I

<160 mmHg: recheck in 3-6 months
J

>180 mmHg: TREAT
What are the 2 goals of SHT tx?
Control BP and treat underlying disease
What do ACEi do to BP?
Decrease 10-15 mmHg
What effect do ACEi have on the renal efferent arteriole?
Decrease glomerular hypertension and proteinuria
What effect do ACEi have on RAAS?
inhibits
What drug class is telmisartan?
AT receptor blocker
What effect does telmisartan have on BP?
Decreases 20-25 mmHg
What effect does telmisartan have on the renal efferent arteriole?
Decreased glomerular hypertension and proteinuria
What effect does telmisartan have on RAAS?
inhibits
What drug class is amlopidine?
Ca channel blocker
What effect does amlopidine have on BP?
Decreases 30-60+ mmHg
What effect does amlodipine have on the renal efferent arteriole?
No effect
What effect does amlodipine have on RAAS?
activates
When should BP be rechecked in non-emergent cases?
7-10d after starting an antihypertensive
What should you do if you recheck a non-emergent BP and it is >140 mmHg?
Increase hypertensive dose or add 2nd agent
What should you do if you recheck a non-emergent BP and it is hypotensive?
Decrease anti-hypertensive dose
What should you do if you recheck a non-emergent BP and it is normotensive?
recheck again q 3-4 months
What should be done in cases of emergent BP issues (i.e. retinal detachment)?
Hospitalization, amlodipine or hydralazine, recheck BP q 2 hours