Bone (lesson 3) Flashcards

1
Q

what can bone tissue also be known as?

A

osseous tissue

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2
Q

Bone tissue is a ____and ____, ____ tissue.

A

dense, supportive, connective

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3
Q

bone tissue contains ______ cells.

A

specialised

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4
Q

what does bone tissue produce?

A

solid matrix of calcium deposits

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5
Q

what fibres will you find bone tissue around?

A

collagen

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6
Q

how many types of cells do bones contain?

A

4

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7
Q

Name an organic compound in bone

A

collagen

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8
Q

bone is a ____ tissue

A

connective

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9
Q

What does the bone’s matrix consist of?

A

collagen fibres for flexibility and tensile strength
calcium for rigidity
hydroxyapatite Ca5(PO4)3 OH

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10
Q

Define ossification

A

The natural process of bone formation and the hardening of muscular tissue into a bony substance.

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11
Q

what can bone formation also be called?

A

osteogenesis

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12
Q

What is the first process in osteogenesis?

A

the development of hyaline cartilage

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13
Q

in the second stage of osteogenesis the hyaline cartilage ______ and the matrix is formed, then some of the matrix is _____.

A

grows, calcified

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14
Q

What is stage 3 in osteogenesis?

A

the development of the primary ossification centre

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15
Q

the primary ossification centre has a _____ bud and ______/____ cavity.

A

periosteal, medullary/marrow

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16
Q

in stage 4 of osteogenesis the development of the _______ _________ ______ in the ______ occurs.

A

secondary ossification centre, epiphysis

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17
Q

in the last stage of bone formation what two things are formed?

A

the articular cartilage and epiphyseal plate

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18
Q

where do bones lengthen?

A

the epiphyseal plate

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19
Q

bones grow from _____.

A

cartilage

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20
Q

When bone growing is complete what forms?

A

the epiphyseal line

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21
Q

Bones undergo constant remodelling from ___ __ ____ and _____.

A

adaption to stress and healing

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22
Q

What is dense/compact bone also known as?

A

cortical bone

23
Q

what percent of bone in our bodies is cortical bone?

A

85%

24
Q

name some components of compact/cortical bone

A
osteon/haversian system
central/haversian canal
lamellae
lacunae with osteocytes
canaliculi
25
Q

what is spongy/cancellous bone known as?

A

trabecular bone

26
Q

What percent of spongy bone do we have in our body (out of all the bones in our body)?

A

15%

27
Q

what is trabecular bone made up of?

A

trabeculae

28
Q

The outer layer of the periosteum is ____ and has an _____ network of _____ and ____ _____.

A

dense, irregular, nerves and blood vessels

29
Q

what cells does the inner layer of the periosteum contain?

A

osteoblasts

30
Q

How is the inner layer of the periosteum anchored to the bone?

A

by collagen fibres that penetrate into the bone

31
Q

What canals connect the Haversian canals and also assist blood supply from the periosteum to the harversian canals?

A

Volkmann’s canals

32
Q

What happens if calcium ion concentration increases by 30%?

A

neurons and muscle cells become unresponsive

33
Q

What happens if calcium ion concentration decreases by 35%?

A

convulsions

34
Q

Death may occur if the calcium ion concentration decreases by _____%.

A

50

35
Q

calcium levels are closely regulated by ____ _________.

A

calcium homeostasis

36
Q

What does PTH do to the kidneys?

A

It decreases the rate of excretion of calcium ions

37
Q

When calcium ion concentration in the blood increases, _______ is released into the blood stream.

A

calcitonin

38
Q

what does calcitonin inhibit?

A

calcitonin inhibits osteoclast activity

39
Q

How does the release of calcitonin affect the kidneys?

A

It increases the rate of excretion of calcium ions

40
Q

Name a nutritional bone disorder

A

rickets

41
Q

As x-rays pass through the body, they are partially _____.

A

absorbed

42
Q

The _____ the tissue, the greater the fraction of radiation that is _____.

A

denser, absorbed

43
Q

What is osteopenia?

A

inadequate ossification

44
Q

The prevalence and severity of osteopenia typically increases with _____.

A

age

45
Q

What body parts are most affected by osteopenia?

A

epiphyses (end of long bones), vertebrae and jaw.

46
Q

What is osteoporosis?

A

The reduction in bone mass sufficient to compromise bone function

47
Q

What can osteoporosis typically lead to?

A

Bone fracture, leads to loss of independence and immobility

48
Q

what gender is osteoporosis most common in (due to hormones)?

A

females

49
Q

What happens immediately after a bone fracture? (stage 1 of fracture healing)

A

Extensive bleeding occurs, over a period of several hours, a large blood clot or fracture hematoma, develops.

50
Q

what is stage 1 of fracture healing known as?

A

Fracture hematoma

51
Q

What is stage 2 of fracture healing?

A

A callus forms

52
Q

In stage 3 _____ occurs, this mean that the external callus becomes replaced by ___.

A

ossification, bone

53
Q

In stage 3 what happens to fragments of dead bone and the areas of bone closest to the break?

A

They are removed and replaced

54
Q

what is the final stage in fracture healing?

A

Remodelling, a swelling initially marks the location of the fracture, over time this region will be remodelled and little evidence of the fracture will remain.