BIOL 437 Week Two Part 1 Flashcards

1
Q

disease

A

-an interpretation or disorder of body functions, systems or organs

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2
Q

diseases arise from

A
  • infectious agents (pathogens)
  • inherent weaknesses
  • environmental stresses
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3
Q

environment

A
  • all that is external to the human host

- physical, social, biological, cultural

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4
Q

‘random’ occurrence of disease

A

-do not occur randomly

>some individuals are more at risk as risk factors are not randomly distributed in the population

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5
Q

epidemiologic triad/triangle

A
  1. Agent
  2. Susceptible host
  3. Environment (now has a major influence)
    * simplest model of disease causation
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6
Q

agent

A
  • infectious micro-organism/pathogen

- toxins, physical forces

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7
Q

chronic diseases with multiple causes

A
  • triad model does not work well

eg. CVD, cancer

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8
Q

infectious microorganisms/pathogen

A
  • virus, parasite, bacterium

- necessary, but not necessarily sufficient alone (ex. dose, pathogenicity)

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9
Q

host

A

-human or animal who can get the disease

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10
Q

risk factors influences

A
  • exposure
  • susceptibility
  • response to agent
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11
Q

examples of risk factors

A
  • behaviours
  • hygiene
  • psychological makeup
  • medications
  • gender
  • age
  • genetics
  • nutrition
  • immune status
  • comorbidity
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12
Q

environment

A

-factors affecting the agent and the opportunity for exposure

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13
Q

examples of environment

A
  • geology
  • climate
  • socioeconomic factors
  • biologic factors (insect vectors)
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14
Q

socioeconomic factors

A
  • crowding
  • sanitation
  • access to health care
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15
Q

primary focus in epidemiology

A
  • identifying the causes of disease

- identify mechanisms by which disease spread

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16
Q

etiology

A

-science and study of the causes of disease and their mode of operation

17
Q

communicability

A

-ability of a disease to be transmitted from one person to another or to spread through the population

18
Q

classify acute and chronic disease according to

A
  • infectivity

- communicability

19
Q

communicable disease

A

-when an infectious disease is contagious or capable of being communicated or transmitted

20
Q

examples of communicable diseases

A
  • HIV/AIDS
  • cholera
  • influenza
  • cryptosporidiosis
21
Q

vertical transmission

A

-transmission from an individual to its offspring through sperm, placenta, milk or vaginal

22
Q

horizontal transmission

A

-transmission of infectious agents from an infected individual to a susceptible peer

23
Q

pathogens

A

-organisms or substances such as prions, bacteria, viruses, fungi, or parasites that are capable of producing diseases

24
Q

invasiveness

A

-the ability to get into a susceptible host and cause diseases

25
Q

virulence

A

-the disease-evoking power of a pathogen

26
Q

toxins

A

-kill pathogens by poisoning them

27
Q

antibiotics

A
  • work against pathogens because of their toxicity

- using bacteria to fight off other bacteria and pathogens

28
Q

acute

A
  • disorder with sudden onset
  • relatively severe
  • short duration of symptoms
29
Q

chronic

A
  • less severe
  • long and continuous duration
  • lasting over long periods, if not a lifetime
30
Q

natural history and spectrum of disease

A
  • progression of disease in a person over time without treatment
  • most diseases have a characteristic natural history
  • appropriate exposure to accumulation of factors sufficient for the disease to start in a susceptible host
31
Q

major stages in the disease process

A
  1. Susceptibility
  2. Pre-symptomatic disease
  3. Clinical disease
  4. Recovery, disability, or death
32
Q

pre-symptomatic disease stage

A
  • incubation period

- latency period

33
Q

susceptible host factors

A
  • genetics
  • specific immunity
  • non-specific defences
  • malnutrition
  • alcoholism
  • concurrent disease: comorbidities