BIOL 437 Measures of Risk Flashcards

1
Q

measures of risk

A
1. Frequency measures
>ratio, proportion, rate
2. Morbidity Frequency Measures
>incidence and prevalence
>mortality rate
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2
Q

frequency measures

A
  • characterize only part of the distribution

- compare one part to another, or to the entire distribution

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3
Q

ratio

A
  • relative magnitude of two quantities
  • comparison of any two values
  • numerator and denominator do not need to be related
  • used as both descriptive measures and analytic tools
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4
Q

death-to-case ratio

A
  • commonly used
  • number of deaths during specific period divided by new cases in same period
  • a measure of severity of an illness
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5
Q

proportion

A
  • comparison of a part to the whole
  • numerator is included in the denominator
  • decimal, fraction or percent
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6
Q

uses of proportions

A
  • used as descriptive measures
  • used to describe the amount of a disease that is attributable to a specific exposure
  • can be converted to ratios
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7
Q

proportionate mortality

A
  • proportion of deaths in a specifed population during a period of time that are attributable to different causes
  • each cause is a percentage of all deaths
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8
Q

rate

A
  • measure of frequency with which an event occurs in a defined population over a specified period of TIME
  • measure of risk
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9
Q

types of rates

A
  • incidence rate: how quickly
  • attack rate: proportion that develops illness
  • prevelance rate: proportion at particular time
  • case-fatality rate: die
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10
Q

morbidity

A

-any departure (subjective or objective) from a state of physiological or psychological well-being
>disease, injury, disability

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11
Q

incidence

A

-occurence of new cases in a population over specific time
>new cases in a community
>new cases per unit of population
ex. incidence proportion or incidence rate

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12
Q

incidence proportion

A
  • attack rate
  • probability of developing a disease (cumulative incidence)
  • proportion of initially disease-free that develops disease during specific time
  • numerator is is denominator
  • used in outbreak setting
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13
Q

types of attack rates

A
  1. Overall attack rate
  2. Food-specific attack rate
  3. Secondary attack rate
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14
Q

secondary attack rate

A

-difference between community transmission vs. transmission within a household or closed population

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15
Q

incidence rate

A
  • person-time rate
  • incorporates time directly into denominator
  • generally applies to long-term cohort follow-up study
  • each person is observed from a set starting time until one of four ‘end points’ is reached
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16
Q

end points

A
  • onset of disease
  • death
  • migration out of study
  • end of study
17
Q

incidence rate is

A

-ratio of number of cases to the total time the population is at risk of disease

18
Q

uses of incidence rate

A
  • describes how quickly disease occurs in a population

- accomadates for persons entering and leaving the study

19
Q

disadvantages of incidence rates

A
  • assumes the probability of disease during the study period is constant
  • long-term cohort studies are not very common
20
Q

prevelance

A
  • sometimes called prevelance rate

- includes all cases, new and pre-existing

21
Q

point prevelance

A

-particular point in time

22
Q

period prevelance

A

-over an interval of time

23
Q

prevelance vs. incidence

A
  • prevelance: HAVE condition, all cases regardless when it began
  • incidence: DEVELOP condition at a particular time, only NEW cases
24
Q

prevelance based on

A
  • incidence
  • duration of illness
  • often a measure of chronic diseases
25
Q

high prevelance

A

-high incidence or prolonged survival without cure OR both

26
Q

low prevelance

A
  • low incidence

- rapidly fatal process or rapid recovery

27
Q

mortality rate

A

-frequency of occurence of death in a defined population during a specified interval