biochemistry - lipid anabolism

Question 1

where does the synthesis of fatty acids occur (lipogenesis)

Answer 1

liver 
kidney
mammary glands 
adipose tissue 
brain

Question 2

t/f lipogenesis is oxidative

Answer 2

false 
electrons required (reductive)

Question 3

during lipogenesis, when excess carbohydrates are taken in, they are converted to fatty acids and triglycerides in the liver, what happens to these products

Answer 3

fatty acids - transported in plasma by binding with albumin

triglycerides - transported to adipose tissue by VLDL for storage

Question 4

what transports acetyl group into the cytoplasm (cannot pass inner mitochondrial membrane)

Answer 4

citrate

Question 5

malonyl-coA is the activated product of acetyl-coA by acetyl-CoA carboxylase, what is dnated to the lipid

Answer 5

carbon atoms

Question 6

lipogenesis can occur by fatty acid synthase, what length does the chain need to be in order to release the fatty acid

Answer 6

C-16

Question 7

what does insulin signal

Answer 7

fed state - storage of fuels and synthesis of proteins

Question 8

what does glucagon signal

Answer 8

starved state

Question 9

what does epinephrine signal

Answer 9

energy requirement

Question 10

what is required for synthesis of triglycerides

Answer 10

glycerol-3-phosphate (G-3-P)

Question 11

what is G-3-P produced from in adipose tissue

Answer 11

glucose

Question 12

how is G-3-P produced in liver

Answer 12

glycerol reacts with glycerol kinase