Biochemistry Flashcards
2 main renal indications of glomerular function?
GFR
proteinuria
problems with using inulin to measure GFR?
endogenous
not easy to measure
creatinine is secreted into the renal tubule T or F
F
what does creatinine actually measure
marker of muscle protein breakdown
what percentage of creatinine is filtered by the kidney?
90-95% filtered
creatinine tends to overestimate the GFR slightly T or F
T
high creatinine indicates renal disease T or F
T
relationship between creatinine and GFR?
as GFR decreases, creatinine will rise
creatinine is more effectively measured when GFR is very high T or F
F, it changes very minimally when GFR is high
how can creatinine measure high GFR levels more clearly?
measure urine creatinine clearance
eGFR is not great at measuring high GFR levels T or F
T
2 methods of measuring levels of proteinuria?
24hr urine collection
spot sample for protein/creatinine ratio
will microalbuminuria show up on dipstick?
no
what dipstick reading will nephrotic syndrome show up as?
3+
what does microalbuminuria mean?
excretion of albumin in abnormal quantities but still below the limit of protein detection
