Adverse Drug Reactions Flashcards
1
Q
cardio drugs with low therapeutic index?
A
warfarin
digoxin
2
Q
what antibiotics have a low therapeutic index?
A
vancomycin
gentamicin
3
Q
a type A drug interaction is…
A
augmented pharmacological effect which is dose dependent
4
Q
which type of drug reaction presents with bizarre, unpredictable effects?
A
type B
5
Q
what type of drug reaction presents with chronic effects
A
type C
6
Q
what drugs can cause tubular necrosis?
A
gentamicin
sulfonamides
aspirin
7
Q
will chemo cause a pre or post renal drug reaction?
A
post renal
8
Q
which type of drug reaction has the highest mortality?
A
B
9
Q
should ACEi be stopped in pregancy? if yes, how long before?
A
yes 4-6 weeks beforehand
10
Q
south asian man with an HLAB5801 mutation is likely to get….
A
stephen johnson syndrome
