Asthma Flashcards

1
Q

what are the three characteristics of asthma

A

bronchioconstriction, mucus accumulation, and membrane inflammation

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2
Q

what is the flow equation

A

change in pressure/resistance

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3
Q

what is the #1 cause of hospitalization of children in the US

A

asthma

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4
Q

explain inappropriate bronchiole spasms

A

episodes of exaggerated bronchiole spams, exercise and pollutants can trigger this(overreaction to stimulus)

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5
Q

explain bronchiole inflammation

A

bronchiole tube becomes swollen and diameter is reduced which causes resistance to flow (1/r^4)

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6
Q

what is inflammation

A

essential response by body, starts the process of healing, an attempt to prevent spreading(trap and localize infection)

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7
Q

four characteristics of inflammation

A

heat, red, swollen, pain

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8
Q

explain excessive mucus production

A

occurs in the bronchioles and is an inappropriate amount, clogs the pores

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9
Q

what do all three characteristics of asthma do

A

make it more difficult for an individual to breathe

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10
Q

what is asthma

A

episodic and chronic

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11
Q

what two ways diagnose asthma

A

forced expiratory volume and peak expiratory flow

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12
Q

what is mucus

A

snot

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13
Q

what is mucous

A

membrane in inner lining of tube

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14
Q

what shows resistance(ml air/sec) due to swelling and mucus

A

FEVI

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15
Q

what is the amount of air that can be pushed out in one second (best measure/diagnosis of asthma)

A

forced expiratory volume

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16
Q

how does FEVI work

A

breathing tube in mouth, breathe, measure volume that can get out in one second

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17
Q

volume of all alveoli added together

A

vital capacity

18
Q

why is vital capacity not good for measuring asthma

A

primary manifestations are in bronchioles not alveoli

19
Q

what is the second best measure of asthma and is the fastest speed in an instant that air can get out of lungs

A

peak expiratory flow

20
Q

what is the average peak expiratory flow for men and women

A

women: 440-450 L/min (6 sec)
men: 600-650 L/min (8sec)

21
Q

how is asthma treated

A

with drugs

22
Q

what is the broad term for drugs targeting acute affects

A

fast acting drugs

23
Q

what do fast acting drugs act via

A

ANS

24
Q

what response do fast acting drugs mimic

A

bronchiodialation

25
Q

describe bronchiodialtion in correspondence with respiration

A

sympathetic nervous division

uses (nor)epinephrine

26
Q

what does the post neuron selectively connect/respond to

A

neurotransmitter receptor on pre neuron

27
Q

what is the name of the fast acting functional name for the class of drugs that mimics the sympathetic division

A

andrenergic-beta agonist receptor

28
Q

describe andrenergic beta agonist receptor

A

stimulator drug that is ONLY bound by adrenaline

29
Q

what happens during a bronchospasm

A

person does not have enough epinephrine receptors

30
Q

what are two commercial drugs used as agonists to replace lack of epinephrine

A

Albuterol and ipratropium bromide (anti-cholinergic)

31
Q

what is cholinergic

A

mimics or inhibits acetylcholine(neurotransmitter of parasympathetic)

32
Q

what do cholinergic drugs do

A

block parasympathetic respiratory response (prevent bronchoconstriction)

33
Q

what is the broad term for drugs that target inflammation or the ANS

A

slow acting asthma drugs

34
Q

what do slow acting drugs target

A

chronic asthma symptoms

35
Q

how are asthmatic drugs taken and why

A

inhaled to target the lungs faster

36
Q

this works by gene activation, slow but powerful

body’s long term stress hormone

A

corticosteroid

37
Q

what does corticosteroid do

A

increases the blood sugar(glucose)and sodium levels in the blood

38
Q

what is the function of corticosteroid

A

effective anti inflammatant(decreases inflammation)

39
Q

what is the actual corticosteroid called

A

beclomethasone

40
Q

describe beclomethasone

A

needs to be taken repeatedly(body breaks it down), affects inflammation every where in body