Asthma Flashcards

1
Q

what are the three characteristics of asthma

A

bronchioconstriction, mucus accumulation, and membrane inflammation

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2
Q

what is the flow equation

A

change in pressure/resistance

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3
Q

what is the #1 cause of hospitalization of children in the US

A

asthma

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4
Q

explain inappropriate bronchiole spasms

A

episodes of exaggerated bronchiole spams, exercise and pollutants can trigger this(overreaction to stimulus)

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5
Q

explain bronchiole inflammation

A

bronchiole tube becomes swollen and diameter is reduced which causes resistance to flow (1/r^4)

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6
Q

what is inflammation

A

essential response by body, starts the process of healing, an attempt to prevent spreading(trap and localize infection)

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7
Q

four characteristics of inflammation

A

heat, red, swollen, pain

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8
Q

explain excessive mucus production

A

occurs in the bronchioles and is an inappropriate amount, clogs the pores

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9
Q

what do all three characteristics of asthma do

A

make it more difficult for an individual to breathe

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10
Q

what is asthma

A

episodic and chronic

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11
Q

what two ways diagnose asthma

A

forced expiratory volume and peak expiratory flow

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12
Q

what is mucus

A

snot

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13
Q

what is mucous

A

membrane in inner lining of tube

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14
Q

what shows resistance(ml air/sec) due to swelling and mucus

A

FEVI

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15
Q

what is the amount of air that can be pushed out in one second (best measure/diagnosis of asthma)

A

forced expiratory volume

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16
Q

how does FEVI work

A

breathing tube in mouth, breathe, measure volume that can get out in one second

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17
Q

volume of all alveoli added together

A

vital capacity

18
Q

why is vital capacity not good for measuring asthma

A

primary manifestations are in bronchioles not alveoli

19
Q

what is the second best measure of asthma and is the fastest speed in an instant that air can get out of lungs

A

peak expiratory flow

20
Q

what is the average peak expiratory flow for men and women

A

women: 440-450 L/min (6 sec)
men: 600-650 L/min (8sec)

21
Q

how is asthma treated

A

with drugs

22
Q

what is the broad term for drugs targeting acute affects

A

fast acting drugs

23
Q

what do fast acting drugs act via

24
Q

what response do fast acting drugs mimic

A

bronchiodialation

25
describe bronchiodialtion in correspondence with respiration
sympathetic nervous division | uses (nor)epinephrine
26
what does the post neuron selectively connect/respond to
neurotransmitter receptor on pre neuron
27
what is the name of the fast acting functional name for the class of drugs that mimics the sympathetic division
andrenergic-beta agonist receptor
28
describe andrenergic beta agonist receptor
stimulator drug that is ONLY bound by adrenaline
29
what happens during a bronchospasm
person does not have enough epinephrine receptors
30
what are two commercial drugs used as agonists to replace lack of epinephrine
Albuterol and ipratropium bromide (anti-cholinergic)
31
what is cholinergic
mimics or inhibits acetylcholine(neurotransmitter of parasympathetic)
32
what do cholinergic drugs do
block parasympathetic respiratory response (prevent bronchoconstriction)
33
what is the broad term for drugs that target inflammation or the ANS
slow acting asthma drugs
34
what do slow acting drugs target
chronic asthma symptoms
35
how are asthmatic drugs taken and why
inhaled to target the lungs faster
36
this works by gene activation, slow but powerful | body's long term stress hormone
corticosteroid
37
what does corticosteroid do
increases the blood sugar(glucose)and sodium levels in the blood
38
what is the function of corticosteroid
effective anti inflammatant(decreases inflammation)
39
what is the actual corticosteroid called
beclomethasone
40
describe beclomethasone
needs to be taken repeatedly(body breaks it down), affects inflammation every where in body