A&P 3.8 Blood/Platelets Flashcards
Transversospinalis
Multifidi
Rotatores
Deep to the erector spinalis muscles
Transverse to spinous
Rotatores are the deepest
Multifidi
Attachment: sacrum and transverse process of the lumbar through cervical vertebrae
Superior attachment: spinous process of lumbar vertebrae through second cervical vertebrae - span 2-4 vertebrae
Action: unilaterally - rotate vertebral column to opposite side
Bilaterally - extend vertebral column
Rotatores
Attachment : transverse processes of the lumbar through cervical vertebrae
Superior attachment: spinous process of lumbar vertebrae through second cervical vertebrae - span 1-2 vertebrae
Action: unilaterally - rotate vertebral column to opposite side
Bilaterally - extend vertebral column
Blood whole
Fluid connective tissue
55% plasma - matrix and fibers present as needed
45% formed elements: RBC, WBC, PLATELETS
Functions of blood
Transportation- nutrients and wastes
Regulation - homeostasis
Protection - clotting, fight infection
Hemopoiesis
Process of creating formed elements
Occurs in blood marrow
MAMA cell of all formed elements is pluripotent stem cell
Formed elements
Red blood cells - no nucleus
White blood cells - have nucleus
Platelets - cell fragments
Pluripotent
Stem cell
Base for all formed elements in blood
Red blood cells
Erythrocytes Live about 120 days Contain hemoglobin - BINDS TO OXYGEN Main job is to carry oxygen STARTS AS A RETICULOCYTE ( before nucleus is ejected)
RETICULOCYTE
Red blood cell before it ejects its nucleus
Ejects nucleus so it can carry more oxygen
Biconcave
Shape of red blood cell when it loses it’s nucleus
Shape allows it to squeeze through tiny capillaries and carry more oxygen
Polycythemia
.Too many red blood cells
Blood is thick and cannot flow well
Platelets
Thrombocytes Cell fragments NO NUCLEUS From MEGAKAROCYTE Normal value is 250,000 per mm of blood Live 5-9 days
MEGAKAROCYTE
Gets really large
Explodes into 2000-3000 fragments
Fragments are platelets
Platelets
Physical properties
Agglutination
Adhesiveness
Aggregation
Agglutination
Adhere and form clumps
Adhesiveness
ability to stick to damaged tissue
Aggregation
Gather together
Platelets
Function
To form platelet plugs in broken blood vessels
Hemostasis
BLOOD STILLNESS
A sequence of responses that stop bleeding
Hemostasis
Sequence
Vascular spasm
Platelet plug formation
Clotting (coagulation)
Vascular spasm
Contraction of SMOOTH MUSCLE in blood vessel wall to reduce the size of the tear in the vessel
Platelet plug formation
Platelets notice the roughness in the EPITHELIAL tissue lining of the blood vessel (endothelium) they slow down, get sticky and send out projections to fill the gap
They also send out a chemical that triggers the formation of fibrous protein threads called fibrin
Clotting
Coagulation
Fibrin threads interweave in platelet plug and close the gap
Conditions that oppose clotting
Anticoagulants
Anticoagulants
Blood thinners
Heparin, warfarin (Coumadin), aspirin
Delay or suppress (or prevent) blood clotting
Conditions that hasten clotting
Atherosclerosis
Antherosclerosis
May hasten clotting
The thickness of the blood and or narrowing of the vessels lumen may slow blood flow and clot blood when it is not necessary
Clotting pathologies
Thrombus
Embolus
Hemophilia
Thrombus
Clotting in an unbroken blood vessel
Usually a vein
Embolus
Blood clot that breaks off and floats through the bloodstream
Embolism
Embolus lodged in a smaller vessel (blocks flow to vital organ)
VENOUS - goes to lungs (pulmonary embolism)
ARTERIAL - goes to coronary vessel - can cause heart attack, stroke, TIA, in the kidneys can lead to a renal infarction
Hemophilia
Deficiency of clotting
Most often due to lack of clotting factor 8 (VIII)
Anemia
Shortage of red blood cells, hemoglobin or both
Pallor, shortness of breath, fatigue, poor resistance to cold
Idiopathic anemia or nutritional deficiency anemia are ok to massage
Bone marrow suppression (cancer), chronic disease/inflammation, or premature red blood cells destruction – rigorous massage may be contraindicated
Energy work more appropriate