A&P 3.7 Red Blood Cells Flashcards
Popliteus
A, O, I
Origin: lateral condyle of the femur
Insertion: posterior proximal tibia - above soleal line
Action: unlocks knee to permit flexion
Deepest muscle of the posterior knee
Popliteus
Plantaris
A, I, o
Sole of the foot
Origin: lateral super condylar ridge of the femur
Insertion: via a long tendon that attaches to the medial Achilles’ tendon and deep fascia of the ankle
Action: assists in plantar flexion of ankle
Runs oblique from lateral to medial
Longest tendon in the body
Plantaris
Short muscle belly but longest tendon in the body
Blood fluid
Whole blood
55% plasma - matrix
45% formed elements - red blood cells, white blood cells, platelets
Men have 5-6 liters
Women have 4-5 liters
Blood formed elements include
Red blood cells
White blood cells
Platelets
Functions of blood
Transportation - of carbon dioxide, hormones, nutrients and waste by PLASMA, OXYGEN BY RED BLOOD CELLS
Regulation- homeostasis- water balance of all cells and temperature regulation
Protection - blood clotting by platelets, defense by white blood cells
Blood plasma
Contents
Makes up 55% of whole blood
It is a matrix of connective tissue
91% is water
9% is solutes
Solutes
Particles dissolved or suspended in water
Formed elements
3
Red blood cells - erythrocytes - whole cells, no nucleus
White blood cells - Leukocytes - whole cells with a nucleus
Platelets - thrombocytes - cell fragments, no nucleus
99% of formed elements are red blood cells
Hematocrit
Is the volume percentage of red blood cells
Average for men is 45%, women is 42 %
Amenia
Defined
Conditions that result in decreased red blood cells are called anemia
Characterized by a decreased hematocrit value
Adults with less than 10 grams of hemoglobin per 100ml of blood is diagnosed as having anemia
Hematopoiesis
Defined
The process of creating formed elements that occur in red bone marrow
Caused by pluripotent stem cells
Also known as hemopoiesis.
Formed elements come from
Pluripotent stem cells
Red blood cells
General
Live about 120 days
Hemoglobin is primary component
Main job is to carry oxygen through the body due to binding of hemoglobin with oxygen
Biconcave - loses it’s nucleus and caves in the middle
Most numerous of formed elements - 99%
Hemoglobin
Pigment that causes blood to appear red
Biconcave
Red blood cell loses it’s nucleus and caves in the middle
Hematopoesis
Another name for hemopoiesis
Hemoglobin
Within each red blood cell are 200-300 million molecules of hemoglobin
One hemoglobin molecule contains four iron (Fe) atoms
Anemias are classified according to she size and hemoglobin content of red blood cells
An adult with less than 10g of hemoglobin per 100ml of blood is diagnosed as having anemia
Destruction of red blood cells
Often break apart or fragment in the capillaries as they age Macrophage cells (type of white blood cell) in the lining of the vessels, liver and spleen phagocytose (ingest and destroy) the aged, abnormal or fragmented red blood cells Leading to the breakdown of hemoglobin with a release of amino acids, iron and the pigment bilirubin
Macrophage
Type of white blood cell
Phagocytose
Ingestion and destruction of cells
Breakdown of hemoglobin releases
Amino acids
Iron
Pigment bilirubin
Red blood destruction becomes
3 things
EXTRA?
Glubin - amino acids
Heme - becomes iron and transferrin
Biliverdin
Destruction of red blood cells continued
Iron is returned to bone marrow for synthesis of new hemoglobin and bilirubin is transported to the liver then excreted into the intestines as part of bile
Amino acids that are released are used by the body for energy or synthesis of new proteins
Blood disorders
Polycythemia
Anemia
Polycythemia
Too many red blood cells
Blood is thick and cannot flow well
Anemia
Shortage of red blood cells, hemoglobin or both
Pallor, shortness of breath, fatigue, poor resistance to cold
Idiopathic anemia or nutritional deficiency anemia are ok to massage
Bone marrow suppression (cancer), chronic disease/inflammation, or premature red blood cells destruction – rigorous massage may be contraindicated
Energy work more appropriate
Massage contraindicated anemias
Aplastic anemia - destruction of red blood cells - contraindicated Acute blood loss anemia Hemolytic anemia (breakage) - sickle cell - African/Latino - thalassemia - Mediterranean
Anemia ok to massage
Iron deficiency anemia
Pernicious anemia - vitamin B12 not absorbed