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Pathology finish > 71. Tumors of the central and peripheral nervous system > Flashcards

71. Tumors of the central and peripheral nervous system Flashcards

1
Q
  1. Tumors of the central and peripheral nervous system

types of CNS tumor (5)

A 
glioma
neuronal tumor
embrynal tumor
meningioma
craniopharayngioma
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2
Q
  1. Tumors of the central and peripheral nervous system

types of glioma (3)

A

astrocytoma
oligodendroglioma
ependymoma

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3
Q
  1. Tumors of the central and peripheral nervous system

types of astrocytoma (4)

A

diffuse astrocytoma
anaplastic astrocytoma
glioblastoma multiforme
pilocytic astrocytoma

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4
Q
  1. Tumors of the central and peripheral nervous system

location, symptom of astrocytoma

A

cerebral hemisphere

seizure, headache, focal neurological defect

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5
Q
  1. Tumors of the central and peripheral nervous system

characteristics of glioblastoma multiforme

  • differentiation
  • location
  • microscopic change
A

poorly differentiated malignant tumor
characteristically across corpus callosum
cause regional necrosis, endothelial cell proliferation

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6
Q
  1. Tumors of the central and peripheral nervous system

characteristics of pilocytic astrocytoma

  • epidemiology
  • location
  • microscopic morphology
A

usually in children
located in cerebellum
cystic lesion, mural nodule

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7
Q
  1. Tumors of the central and peripheral nervous system

molecular marker of glioma

A

GFAP (glial fibrillary acidic protein)

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8
Q
  1. Tumors of the central and peripheral nervous system

characteristics of oligodendroglioma

  • gross morphology
  • microscopic morphology
A

calcific tumor on white matter

fried-egg appearance

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9
Q
  1. Tumors of the central and peripheral nervous system

characteristics of ependymoma

  • origin, location
  • epidemiology
A

ependymal cell, usually in 4th ventricle

children, cause hydrocephalus

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10
Q
  1. Tumors of the central and peripheral nervous system

types of neuronal tumor (2)

A

neurocytoma

ganglioglioma

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11
Q
  1. Tumors of the central and peripheral nervous system

characteristics of ganglioglioma

  • location
  • symptom
A

mostly in temporal lobe

epilepsy seizure

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12
Q
  1. Tumors of the central and peripheral nervous system

characteristics of neurocytoma
- location (2)

A

central (intraventricular)

extraventricular

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13
Q
  1. Tumors of the central and peripheral nervous system

characteristics of medulloblastoma

  • origin, location
  • epidemiology
A 
granular cell (small round blue cell) of cerebellum
children
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14
Q
  1. Tumors of the central and peripheral nervous system

characteristics of medulloblastoma

  • clinical manifestation
  • malignancy
A

increases intracranial pressure, cause hydrocephalus

aggressive, spread to leptomeninges & CSF

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15
Q
  1. Tumors of the central and peripheral nervous system

characteristics of meningioma

  • origin, location
  • risk factor
A

(most common benign brain tumor)
arachnoid cell, attached on dura mater
female, head & neck irradiation, NF2 gene lost in chr. 22

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16
Q
  1. Tumors of the central and peripheral nervous system

characteristics of chraniopharyngioma

  • location
  • clinical manifestation
A

sellar origin af rathke’s pouch

compress optic chiasm, cause bitemporal hemianopsia

17
Q
  1. Tumors of the central and peripheral nervous system

types of PNS tumor (3)

A

schwannoma
neurofibroma
malignant peripheral nerve sheath tumor (MPNST)

18
Q
  1. Tumors of the central and peripheral nervous system

characteristics of schwannoma

  • location
  • clinical manifestation
A

(most common PNS tumor)
cranial nerve 8 (vestibular nerve)
cause hearing loss, tinnitus

19
Q
  1. Tumors of the central and peripheral nervous system

types of neurofibroma (2)

A

cutaneous/solitary

plexiform

20
Q
  1. Tumors of the central and peripheral nervous system

characteristics of cutaneous neurofibroma

  • location
  • form
A

skin

nodule, hyperpigmented, maccule

21
Q
  1. Tumors of the central and peripheral nervous system

characteristics of plexiform neurofibroma

A

potential malignancy

22
Q
  1. Tumors of the central and peripheral nervous system

characteristics of MPNST

  • origin
  • malignancy
A

from plexiform neurofibroma

locally invasive, metastatic spread

Pathology finish (30 decks)

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