46. pathology of pregnancy (dysfunctions of implantation, trophoblastic tumors) Flashcards
46-1. dysfunction of implantation
order of most common place of ectopic pregnancy
oviduct, ovary, abdomen
46-1. dysfunction of implantation
predisposing factor of ectopic pregnancy (2)
pelvic inflammatory disease
endometriosis
46-1. dysfunction of implantation
complications of ectopic pregnancy (2)
hematosalpinx
rupture
46-2. trophoblastic tumor
types of trophoblastic tumor (3)
hydatidiform mole
invasive mole
choriocarcinoma
46-2. trophoblastic tumor
morphology of hydatidiform mole
mass of swollen, dilated chorionic villi
46-2. trophoblastic tumor
types of hydatidiform mole
complete mole
partial mole
46-2. trophoblastic tumor
characteristics of complete hydatidiform mole (4)
empty ovum + 2 sperm
diploid
cannot embryogenesis (no fetal tissue)
only composed of abnormal villi
46-2. trophoblastic tumor
characteristics of partial hydatidiform mole (4)
normal ovum + 2 sperm
triploidy
with early embryogenesis (presence of fetal tissue)
presence of normal villi
46-2. trophoblastic tumor
characteristics of invasive mole
local invasive complete hydatidiform mole
46-2. trophoblastic tumor
invasion part of invasive mole (2)
broad ligament
vagina
46-2. trophoblastic tumor
etiology of choriocarcinoma
under 20 years old or over 40 years old, asian and afreecan
46-2. trophoblastic tumor
clinical features of choriocarcinoma (2)
bloody discharge
increased hCG
46-2. trophoblastic tumor
metastasis of choriocarcinoma
hematogenous metastasis
lung, vagina, brain, liver, kidney