55. Pathology of the hypothalamic-hypophysis system Flashcards
- Pathology of the hypothalamic-hypophysis system
etiology of hyperpituitarism (2)
pituitary adenoma
extrapituitary tumor
- Pathology of the hypothalamic-hypophysis system
subtypes of pituitary adenoma
functional - prolactinoma - somatotroph adenoma - corticotroph adenoa - gonadotroph adenoma - thyrotroph adenoma non functional
- Pathology of the hypothalamic-hypophysis system
clinical manifestation of prolactinoma (4)
galactorrhea
amenorrhea
loss of libido
headache
- Pathology of the hypothalamic-hypophysis system
clinical manifestation of somatotroph adenoma (2)
gigantism (child)
acromegaly (adult)
- Pathology of the hypothalamic-hypophysis system
clinical manifestation of corticotroph adenoma
cushing syndrome
- Pathology of the hypothalamic-hypophysis system
etiology of hypopituitarism (2)
physical damage : cause empty sella syndrome (enlargemet of bone around pituitary)
sheehan syndrome : pregnancy related infarction
- Pathology of the hypothalamic-hypophysis system
hyperfunction of posterior pituitary (2)
syndrome of inappropriate ADH : excessive ADH cause water retention
paraneoplasia (small cell carcinoma) : ectopic ADH secretion
- Pathology of the hypothalamic-hypophysis system
hypofunction of posterior pituitary
Diabetes insipidus (due to decreased ADH)